Compare the UK's top medicated weight-loss programmes. Second Nature, Voy, Juniper, Numan, and Piko compared on evidence, support, and pricing for 2026.

Mounjaro and Wegovy 7.2 mg are the most effective weight-loss injections in the UK in 2026. Compare efficacy, updated costs, side effects, and NHS access.

Piko vs Second Nature compared. See how clinical evidence, NHS partnerships, support, and pricing differ between these UK weight-loss programmes.

Juniper vs Second Nature compared. NHS partnerships, clinical evidence, dietitian support, and reviews show how these UK weight-loss programmes differ.

Voy vs Second Nature compared. See how clinical evidence, NHS partnerships, dietitian support, & reviews differ between these weight-loss programmes.

Numan vs Second Nature compared. See how NHS commissioning, clinical evidence, coaching, and programme design differ between these UK providers.

Wegovy costs £149-£249 monthly at Second Nature. Compare UK prices, NHS options, & find out why our support increases weight loss by ~40%

Clinical trials suggest Mounjaro leads to more weight loss than Wegovy. Second Nature's recent research suggests Wegovy offers comparable results.

You can take Mounjaro if you have IBS. However, it's recommended to monitor IBS symptoms and stay in touch with your healthcare team during weight loss.

You can take Mounjaro with multiple sclerosis but you should lose weight slowly and continue to monitor your symptoms with your healthcare team.