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Weight-loss medications
Evidence-based guidance on weight-loss medications including GLP-1 receptor agonists like Wegovy, Ozempic, and Mounjaro. Find reliable information on efficacy, side effects, NHS availability, and how these medications work as part of a balanced approach to weight loss. Our content is developed by healthcare professionals and nutritionists to support informed decisions about medication-assisted weight loss in the UK.
Weight-loss medications
How much weight can you lose in a month on Foundayo?
You can expect to lose around 1–2% of your body weight in the first month on Foundayo. Learn what affects your results and why weight loss varies.
Weight-loss medications
How much does Foundayo cost in the UK?
Foundayo will cost £129 to £179 a month in the UK on a private prescription. See prices by dose, how it compares with the Wegovy pill, and NHS access.
Weight-loss medications
The Wegovy pill vs Foundayo: which oral GLP-1 medication is better for weight loss?
Wegovy pill vs Foundayo: 13.6% vs 11.2% average weight loss in trials. Wegovy pill needs to be taken on an empty stomach; Foundayo can be taken any time.
Weight-loss medications
Can you get Foundayo on the NHS?
You can't get Foundayo (orforglipron) on the NHS yet, but a NICE recommendation is expected in November 2026. Learn more about your options here.
Weight-loss medications
Can you buy Foundayo online in the UK?
You can pre-order Foundayo now from online private providers like Second Nature. Learn about weight loss, side effects, and maintenance.
Weight-loss medications
Does Wegovy help you drink less alcohol?
Wegovy appears to reduce how much alcohol people drink. How it affects cravings and hangovers, and what drinking safely on it looks like.
Weight-loss medications
Foundayo (orforglipron): what it is, how it works, and when it’s coming to the UK
Foundayo (orforglipron) is a daily GLP-1 pill for weight loss (11.2%) with no fasting requirements. MHRA approved for UK use on August 10th 2026.
Weight-loss medications
Can oral weight-loss medications help you maintain weight loss after Mounjaro or Wegovy?
ATTAIN-MAINTAIN trial: people who switched from Mounjaro or Wegovy injections to Foundayo kept 75-79% of their weight loss. Now approved in the UK.
Weight-loss medications
Wegovy and tingling hands: the dysaesthesia side effect explained
Tingling on Wegovy affected 22.9% of people on 7.2 mg and 6.0% on 2.4 mg in the STEP UP trial. Why it happens, and when to speak to your prescriber.
Weight-loss medications
Can you get Ozempic on the NHS?
Ozempic is only available on the NHS for type 2 diabetes, not weight loss. Wegovy and Mounjaro are the UK's licensed weight-loss injections.
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