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Knowledge is power. Get all the information you need to get on track – and stay there.
Can you take Mounjaro if you have chronic kidney disease (CKD)?

Weight-loss medications

Can you take Mounjaro if you have chronic kidney disease (CKD)?

You can take Mounjaro with chronic kidney disease (CKD), but only under medical supervision. Second Nature doesn't accept patients with CKD. Find out more.

Can you take Mounjaro if you don’t have a gallbladder?

Weight-Loss Injections

Can you take Mounjaro if you don’t have a gallbladder?

You can take Mounjaro without a gallbladder if your BMI is >27. Expert guidance on safety, managing side effects, & preventing post-surgery diarrhoea.

Can you take Mounjaro with hypothyroidism?

Weight-Loss Injections

Can you take Mounjaro with hypothyroidism?

You can take Mounjaro with hypothyroidism when thyroid levels are well-controlled. Learn about timing, monitoring, & safety considerations.

Can I take painkillers while on Wegovy?

Wegovy compatibility

Can I take painkillers while on Wegovy?

Can you take painkillers with Wegovy? Yes. Paracetamol is safest, NSAIDs need food, and codeine increases constipation risk. Full guide with UK guidance.

Why GLP-1 medications work better for some people than others

Current Health

Why GLP-1 medications work better for some people than others

A Nature study of 27,885 people identified gene variants that predict GLP-1 weight loss and nausea risk, including one specific to Mounjaro users.

Can you take Wegovy with anxiety?

Wegovy compatibility

Can you take Wegovy with anxiety?

Yes, there's no interaction between Wegovy and anxiety medications like SSRIs. How to tell Wegovy side effects apart from anxiety symptoms.

Can you take Wegovy while on statins?

Wegovy compatibility

Can you take Wegovy while on statins?

Yes, no interaction between Wegovy and statins. The SELECT trial showed a 20% reduction in cardiovascular events on top of statin therapy.

GLP-1 muscle and protein planner: maintain muscle while losing weight

Weight-loss medications

GLP-1 muscle and protein planner: maintain muscle while losing weight

Without resistance training, up to 40% of weight lost on GLP-1 medications can be muscle. Get a free personalised protein and exercise plan.

Foundayo (orforglipron): what it is, how it works, and when it’s coming to the UK

Weight-loss medications

Foundayo (orforglipron): what it is, how it works, and when it’s coming to the UK

Foundayo (orforglipron) is a daily GLP-1 pill for weight loss with no fasting requirements. FDA-approved April 2026. Average weight loss 11.2% at 72 weeks.

Mounjaro and Wegovy week-by-week: what to expect at every stage

Weight-loss medications

Mounjaro and Wegovy week-by-week: what to expect at every stage

What to expect on Mounjaro & Wegovy week-by-week, based on clinical data. Includes weight loss, dose schedules, plateau advice, & an interactive timeline.

Make losing weight feel Second Nature

The first step on your Second Nature journey is to take our health quiz.

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