This article is accurate to the best of our knowledge as of May 2025.
When choosing between Second Nature and Curate Health for medication-supported weight loss, the most important difference is programme depth and clinical support.
At Second Nature, we’ve been delivering NHS-commissioned weight-loss services since 2017, combining medication with comprehensive habit-change support from registered dietitians and nutritionists.
In contrast, Curate Health positions itself as a medication provider offering competitive pricing on weight-loss injections with basic clinical oversight but limited behavioural support.
Both services provide access to effective weight-loss medications, but Second Nature’s comprehensive approach provides greater peace of mind for patients seeking clinically-proven support for sustainable weight loss.
The most significant differences between these programmes are:
- Core approach: At Second Nature, we build sustainable habits through behavioural psychology alongside medication, while Curate Health focuses on medication provision with minimal ongoing support
- Clinical support: We provide registered dietitians and nutritionists with GLP-1 expertise, while Curate Health offers basic clinician check-ins with unclear frequency and format
- NHS partnership: We’ve been delivering NHS-commissioned services since 2017 with peer-reviewed outcomes, while Curate Health operates as a private service without NHS programmes
- Long-term planning: We focus on sustainable habit formation for life after medication, while Curate Health’s approach centres primarily on medication management
This guide will help you understand which approach aligns better with your health goals, preferences, and budget.
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Second Nature vs Curate Health: At-a-glance comparison
Feature | Second Nature | Curate Health |
---|---|---|
Core Approach | Psychology-based habit formation alongside medication | Medication-first with minimal behavioural support |
NHS Partnership | NHS-commissioned since 2017, used by over half of UK Health Boards | GPhC-licensed pharmacy, no NHS programmes |
Clinical Evidence | Multiple peer-reviewed publications showing 6.2kg average weight loss at 12 months | Relies on drug trial data for effectiveness claims |
Health Support | UK-registered dietitians and nutritionists with GLP-1 expertise | Basic clinician check-ins (frequency and format unclear) |
Medication Options | Mounjaro | Wegovy, Mounjaro |
Digital Tools | Custom-built app with tracking, recipes, and education | Basic resources with limited educational content |
Weight Loss Claims | 6.2kg average at 12 months (NHS trial); 6.5kg after 12 weeks on medication | References medication trial data (e.g., Wegovy’s 15% weight loss) |
Monthly Cost | £229-£299/month (all-inclusive with £100 off the first month) | £149-£253/month (medication only) |
Post-medication Planning | Comprehensive transition strategies and ongoing support | Self-managed approach with limited guidance |
User Satisfaction | 4.6/5 from 7,600+ Trustpilot reviews | 3.9/5 from 7,800+ Trustpilot reviews |
Clinical credibility & NHS partnership
The foundation of any effective weight management programme lies in its clinical validation and evidence base. This becomes especially important when medication is involved.
Second Nature: NHS-trusted approach
At Second Nature, we’ve built our reputation on a strong foundation of clinical trust and evidence since our inception.
Since 2017, the NHS has commissioned us to deliver weight loss and type 2 diabetes programmes across the UK, with two-thirds of UK NHS Health and Care boards now using our services.
This partnership with the NHS reflects the confidence healthcare professionals place in our approach, which is grounded in behaviour change psychology and sustainable habit formation.
The effectiveness of our approach is supported by peer-reviewed research published in the British Medical Journal:
- Our members lose an average of 5.9kg at 12 weeks
- 62.5% achieved at least 5% weight loss by 3 months
- 40% of type 2 diabetes patients reduced HbA1c below diagnostic thresholds
More recently, we published research on our medication-supported programme in JMIR Formative Research, showing participants lost an average of 6.5kg (6.4% of body weight) after 3 months, with 62.5% achieving at least 5% weight loss.
Curate Health: Medication-focused provider
Curate Health operates as a GPhC-licensed pharmacy providing access to weight-loss medications with basic clinical oversight.
Their approach centres on medication provision with advertised support from a clinician, though it’s unclear how often this support can be accessed and whether it’s delivered via phone call, text, or other means.
For their weight loss outcomes, Curate Health primarily references drug trial data (e.g., Wegovy’s 15% weight loss in clinical studies) rather than data specific to their service provision or programme effectiveness.
While they provide medication at competitive prices with discreet home delivery, there’s limited programme-specific research examining their effectiveness compared to medication-only approaches.
Programme structure & philosophy
The underlying philosophy of a weight-loss programme profoundly influences not just your immediate results, but your relationship with food, body, and health for years to come.
Second Nature: Building sustainable habits alongside medication
At Second Nature, our programme is built on a foundation of behavioural science, developed through years of NHS collaboration.
We recognise that lasting weight loss requires more than willpower or medication alone.
Rather than focusing solely on medication effects, we help you understand the complex interplay between your biology, psychology, and environment that influences eating patterns and weight.
Our comprehensive approach includes:
- Building sustainable habits that work with your unique body and lifestyle
- A non-restrictive nutrition philosophy that doesn’t require calorie counting
- Structured educational content based on clinical evidence
- An intuitive app with food journals, recipes, and progress tracking
- Supportive peer groups with others on similar journeys
- Both medication-supported and non-medication options
Our framework acknowledges that weight management isn’t simply about willpower or discipline; it’s about creating an ecosystem of habits and understanding supporting your health in the long term.
We view medication as a powerful tool that works best when combined with sustainable lifestyle changes.
Curate Health: Medication-focused approach
Curate Health positions itself as a medication provider with a streamlined approach:
- Focus on providing medications at competitive prices
- Online consultation followed by medication delivery
- Advertised clinician support (frequency and format unclear from website information)
- Basic educational resources with limited content
- Self-managed weight loss approach
- Discreet home delivery with free accessories
- Optional blood testing for eligibility assessment
Their approach appears particularly suited to individuals who prefer independent management of their weight loss journey with medication support but minimal ongoing programme structure.
Support & coaching
When taking weight-loss medications like Mounjaro or Wegovy, having the right support transforms your experience, helping you navigate side effects, adjust your eating patterns, and maintain motivation through challenges.
Second Nature: Professional guidance and peer support
At Second Nature, we provide access to UK-registered dietitians and nutritionists who specialise in supporting members on weight-loss injections.
These qualified professionals are available five days a week via both group and private chat as part of your standard programme cost.
Our health coaches receive specific training in side effect management, ensuring you receive personalised guidance through the physical and emotional challenges that sometimes arise during medication treatment.
We place you in a small group with others on similar journeys, creating a supportive community where you can share experiences and strategies.
This community aspect provides emotional support that’s crucial for long-term success.
Our programme is explicitly designed with post-medication life in mind:
- Focus on sustainable habit formation from your very first day
- Personalised transition plans for maintaining results after medication
- Ongoing access to support resources even after completing the programme
- Community support from others at similar stages
Curate Health: Basic clinical oversight
Curate Health offers fundamental support focused on medication management:
- Advertised clinician support with unclear frequency and delivery method
- Basic educational resources and generic diet advice
- Discreet medication delivery service
- Optional blood testing for treatment eligibility
Their approach relies primarily on patient self-management, with the assumption that individuals can independently navigate their weight loss journey using the provided medication and limited resources.
This can work for highly motivated individuals who prefer minimal programme structure and are confident in managing their own dietary and lifestyle changes, though it may leave some users feeling unsupported during challenging phases of their journey.
Pricing & accessibility
Understanding the full financial commitment helps you make an informed decision that aligns with both your health goals and financial circumstances.
Comprehensive pricing overview
Second Nature options:
- Without medication: £28-£38/month after £9.99 trial
- With Mounjaro: £229-£299 monthly (£100 off the first month; increases with higher doses)
- Minimum commitment: £9.99 (14-day trial) for non-medication programme
Curate Health pricing:
- Wegovy: £149-£253/month (dose-dependent, medication only)
- Mounjaro: £150-£210/month (dose-dependent, medication only)
- Optional blood test: £99 for eligibility assessment
- Additional accessories: Free delivery with basic accessories
While Curate Health’s medication pricing appears lower, the difference reflects what’s included in each service.
At Second Nature, our monthly fee includes:
- Medication costs and delivery
- Full access to our app with 300+ recipes
- Support from our registered dietitians and nutritionists
- Placement in peer support groups
- All educational content and habit-forming tools
- Post-medication transition planning
Curate Health’s offering includes:
- Medication costs and delivery
- Basic clinical oversight (frequency unclear)
- Limited educational resources
- Discreet delivery service
Long-term outcomes
The true measure of any weight management programme lies not just in initial weight loss, but in sustainable health improvements that enhance your quality of life for years to come.
Second Nature: Building for lasting results
At Second Nature, our outcomes approach focuses on:
- Sustainable weight loss: 6.2kg average at 12 months (NHS trial); 6.5kg after 12 weeks on our medication programme
- Metabolic health: Improving broader markers beyond just weight
- Habit formation: Creating enduring lifestyle patterns that support health
- User satisfaction: 4.6/5 on Trustpilot across 7,600+ reviews
- Post-medication planning: Comprehensive strategies for maintaining results long-term
Our approach acknowledges that while dramatic weight loss makes compelling marketing, more moderate, sustainable changes often lead to better long-term health outcomes.
We’ve seen that without proper support, many people regain weight after stopping medication. That’s why we help you build the psychological and practical foundations for lasting success.
Curate Health: Medication-focused outcomes
Curate Health emphasises:
- Medication effectiveness: References clinical trial outcomes (e.g., Wegovy’s 15% weight loss in studies)
- Cost efficiency: Lower medication costs enabling longer treatment periods
- User satisfaction: 3.9/5 on Trustpilot from 7,800+ reviews
- Accessibility: Competitive pricing and streamlined prescription process
Their outcomes primarily reflect medication effectiveness rather than programme-specific results, with success largely dependent on individual self-management capabilities.
Take home message
Weight-loss medications like Mounjaro can be life changing when used appropriately. The key question is whether you want medication alone or medication combined with comprehensive support for lasting change.
Your choice between Second Nature and Curate Health should reflect your personal health philosophy, support preferences, and long-term goals.
Choose Second Nature if you value:
- Evidence-based approach: NHS partnership and peer-reviewed clinical outcomes providing peace of mind
- Comprehensive support: UK-registered dietitians with extensive GLP-1 medication expertise
- Sustainable philosophy: Learning habits that last beyond medication
- Community support: Peer groups and ongoing professional guidance
- Post-medication planning: Comprehensive strategies for life after medication
- Holistic approach: Psychology-based understanding of eating behaviours
- Higher satisfaction scores: Proven track record across thousands of reviews
Choose Curate Health if you value:
- Cost efficiency: Lower medication costs for budget-conscious users
- Self-management: Confidence in managing your own weight loss journey
- Simplicity: Streamlined medication provision without programme complexity
- Quick access: Fast prescription process with minimal requirements
- Discreet service: Private delivery with basic clinical oversight
At Second Nature, we believe sustainable weight management continues long after medication use ends. Our programme teaches you how to build a healthier relationship with food and your body through understanding habits, not just relying on medication effects.
If you’ve tried multiple approaches to weight loss and want comprehensive support for lasting change, our NHS-validated approach provides the foundation for sustainable success.
If you’re confident in self-managing your weight loss journey and primarily need access to affordable medication with basic oversight, Curate Health offers a cost-effective solution.
Remember that the ultimate goal isn’t just weight loss, but creating a healthier relationship with your body that supports your wellbeing for life.
Ready to start your journey with Second Nature?
Second Nature’s medication programme
At Second Nature, we provide Mounjaro as part of our medication-supported weight-loss programme.
Why should you choose Second Nature over other medication providers if you’ve decided to try Mounjaro (assuming you’re eligible)?
For peace of mind.
We’ve worked with the NHS for over 6 years, providing weight-loss programmes across the UK.
While our Mounjaro weight-loss programme is private and not currently used by the NHS, we’ve built it focusing on scientific evidence, patient safety, and data security.
We hope that our 6+ years of working with the NHS and building a track record of effective weight-loss results will give you peace of mind to give us a try.