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Do you need to take electrolytes while on Mounjaro?

Robbie Puddick (RNutr)
Written by

Robbie Puddick (RNutr)

Content and SEO Lead

Medically reviewed by

Dr Rachel Hall (MBCHB)

Principal Doctor

6 min read
Last updated June 2025
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Jump to: Why you might need electrolytes | The electrolyte supplement reality | Food vs supplements comparison | Managing electrolytes naturally | Take home message

Most people taking Mounjaro (tirzepatide) don’t need electrolyte supplements if they maintain a balanced diet and stay hydrated.

Despite what sports drink companies suggest, research shows that most people get adequate electrolytes from the foods and beverages they consume already.

The colourful powders and expensive drinks marketed as ‘essential’ are rarely necessary for people losing weight on medication.

However, some individuals might benefit from electrolyte supplements during the first few weeks of treatment when stomach issues like nausea or diarrhoea are more common.

Research suggests rapid weight loss, especially when accompanied by stomach problems, can affect your body’s electrolyte balance.

Understanding when electrolytes are actually necessary – versus when the industry wants you to think they are – helps you make informed decisions about your health approach to weight loss on Mounjaro.

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Why you might need electrolytes on Mounjaro

While Mounjaro doesn’t directly cause electrolyte imbalances, several factors during treatment might affect your levels:

Reduced food intake: Mounjaro works partly by decreasing appetite, which might lead to consuming fewer electrolyte-rich foods.

Stomach issues: Some people experience nausea, vomiting, or diarrhoea, particularly in the first few weeks. These symptoms can affect electrolyte balance.

Changes in fluid balance: As your body adjusts to the medication and loses weight, your hydration needs might change.

What electrolytes actually do

Think of electrolytes as the minerals that help your muscles and nerves work properly. These essential minerals come from our food and fluids and are responsible for:

  • Keeping you properly hydrated
  • Helping your muscles contract (including your heart)
  • Supporting nerve signals
  • Maintaining healthy blood pressure
  • Helping nutrients move around your body

The main electrolytes your body needs include sodium, potassium, magnesium, calcium, and chloride. Each plays a specific role in keeping you healthy.

The electrolyte supplement reality

The sports drink industry has successfully convinced many people that expensive powders and neon-coloured drinks are essential for health. The reality is quite different.

Most people don’t need them

Generally, there’s no need for electrolyte supplementation for activities lasting less than 75 minutes, and you can simply hydrate with plain water.

For people taking Mounjaro, this means that unless you’re experiencing significant stomach problems or losing weight very rapidly, your normal diet provides everything you need.

The overuse problem

Overuse of electrolyte drinks can be a problem. Excess electrolytes can lead to heart rhythm issues, fatigue, nausea and more.

Ironically, many symptoms of taking too much look exactly like getting too little.

The supplement industry profits from making healthy people worry about imaginary deficiencies.

Most electrolyte products are simply expensive flavoured water with added salt.

Marketing vs reality

Sports drink companies spend millions convincing us we need their products for basic daily activities. The truth is that your morning coffee with a bowl of yoghurt, fruit, and nuts provides you with everything you need to start your day.

These products target our desire for quick fixes and easy solutions, when the real answer is usually much simpler and cheaper.

Food vs supplements: cost and effectiveness comparison

Whole foods provide superior electrolytes at lower costs than supplements, with better absorption and additional nutritional benefits.

Electrolyte Monthly supplement cost Food alternative Monthly food cost Additional benefits
Sodium (daily needs) £15-25 Pinch of sea salt on meals £1-2 Flavour enhancement
Potassium (3,500mg daily) £20-30 1 banana + 1 potato daily £8-12 Fibre and vitamin C
Magnesium (400mg daily) £12-18 30g almonds + leafy greens daily £10-15 Healthy fats, protein, vitamin E
Calcium (1,000mg daily) £10-15 200ml milk + 30g cheese daily £12-15 Protein, B vitamins, satisfaction
Complete electrolyte blend £35-50 Varied whole food diet £50-80 per person Hundreds of beneficial compounds

Why food is the best option

Better absorption: Your body recognises electrolytes in food more easily than isolated minerals in powders. The potassium in a banana comes with fibre and natural sugars that help your body use it effectively.

No competition issues: Whole foods contain electrolytes in ratios your body expects, so they don’t interfere with each other’s absorption like high-dose supplements can.

Satisfaction factor: Eating electrolyte-rich foods helps you feel full and satisfied. Drinking expensive powders while eating a diet based on ultra-processed foods may leave you hungry and undernourished.

Real-world example:

Instead of spending £40 monthly on electrolyte supplements, invest that money in:

  • Better quality vegetables and fruits (£12-15)
  • Higher-grade dairy or plant-based alternatives (£8-10)
  • Nuts, seeds, or whole grains (£8-10)
  • Good quality sea salt for cooking (£2-3)

You’ll get superior nutrition, feel more satisfied, and save money while developing sustainable eating habits.

Managing electrolytes naturally on Mounjaro

The best approach to maintaining electrolyte balance while on Mounjaro focuses on food and proper hydration rather than expensive supplements.

Focus on electrolyte-rich foods

Include these practical options in your daily meals:

Sodium and chloride: Add a pinch of sea salt to your cooking. One teaspoon provides about 2,300mg of sodium (your daily needs) and costs about 2p.

Potassium (aim for 200-300mg per meal):

  • Half a banana (200mg potassium, 15p)
  • Small baked potato with skin (300mg potassium, 25p)
  • 150g cooked spinach (420mg potassium, 40p)

Magnesium (aim for 100mg per meal):

  • 30g almonds (80mg magnesium, 60p)
  • 100g cooked brown rice (40mg magnesium, 20p)
  • 200g leafy greens (60mg magnesium, 50p)

Calcium (aim for 300mg per meal):

  • 150g natural yoghurt (180mg calcium, 40p)
  • 200ml milk (240mg calcium, 30p)
  • 30g cheese (200mg calcium, 80p)

Stay properly hydrated

  • Aim for 2-2.5 litres of fluid daily from water, herbal teas, and food
  • Increase intake during exercise or hot weather
  • Add a pinch of salt to your water if you’re feeling dizzy or fatigued

Monitor your actual needs

Pay attention to how you feel rather than following supplement marketing:

Signs you’re getting enough: Stable energy, no unusual muscle cramping, feeling satisfied after meals, normal bathroom habits.

Signs you might need more: Persistent muscle cramps, feeling dizzy when standing up, unusual fatigue beyond normal weight loss adjustment.

When supplements might help

Consider discussing electrolyte supplements with your healthcare provider if you:

  • Experience prolonged stomach problems from Mounjaro
  • Consistently feel the signs mentioned above despite eating well
  • Have underlying health conditions affecting electrolyte balance
  • Are exercising intensely for more than 75 minutes in hot conditions

If you choose supplements

Should you decide to try electrolyte supplements:

Choose basic, sugar-free options rather than expensive ‘proprietary blends’. Look for products that contain around 200-300mg sodium, 100-200mg potassium, and 50-100mg magnesium per serving.

Try taking one with breakfast and monitor how you feel. Many people find that adding a pinch of salt to their morning water works just as well as expensive powders.

Remember that more isn’t better with electrolytes. Stick to recommended amounts rather than megadoses.

Take home message

The electrolyte supplement industry profits from making healthy people worry about imaginary deficiencies. Most people taking Mounjaro get everything they need from food and water.

Rather than spending £35+ monthly on colourful drinks and powders, invest that money in quality whole foods that provide superior electrolytes along with essential nutrients you can’t get from supplements.

If you genuinely experience persistent symptoms that might indicate electrolyte imbalance, try adding a pinch of salt to your water and eating more potassium-rich foods before turning to expensive supplements.

Remember that sustainable weight loss comes from developing healthy eating habits, not from relying on the supplement industry’s expensive promises.

Mounjaro works best alongside real nutrition, not processed powders.

Second Nature's Mounjaro programme

Second Nature provides Mounjaro as part of our Mounjaro weight-loss programme

Why choose Second Nature over other medication providers, assuming you’re eligible?

Because peace of mind matters.

We’ve had the privilege of working with the NHS for over eight years, helping people across the UK take meaningful steps toward a healthier, happier life.

Our programmes are designed to meet people where they are, whether that means support with weight loss through compassionate one-to-one health coaching, or access to the latest weight-loss medications (like Mounjaro) delivered alongside expert care from a multidisciplinary team of doctors, psychologists, dietitians, and personal trainers.

At the heart of everything we do is a simple belief: real, lasting change comes from building better habits, not relying on quick fixes. We’re here to support that change every step of the way.

With over a decade of experience, thousands of lives changed, and a long-standing record of delivering programmes used by the NHS, we believe we're the UK’s most trusted weight-loss programme.

We hope to offer you something invaluable: peace of mind, and the support you need to take that first step.

Medication-assisted weight loss with a future focus

Start with Mounjaro, transition to habit-based health with our support

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