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The best weight-loss injections in 2024

Robbie Puddick
Written by

Robbie Puddick

Medically reviewed by

Fiona Moncrieff

4 min read
Last updated June 2024
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Jump to: 1. Tirzepatide | 2. Semaglutide | 3. Liraglutide | Weight-loss injections aren’t a magic pill

Based on data from randomised controlled trials (the gold standard of medical research), the best weight-loss injection that’s available in the UK in 2024 is called tirzepatide, sold under the brand name Mounjaro in the UK.

Research has shown that Mounjaro supports an average weight loss of around 25% after one year.

Other options available in the UK are semaglutide and liraglutide. Below, we’ve ranked the top three weight-loss injections that are available in the UK in 2024.

  1. Tirzepatide (Mounjaro): Average weight loss of 25%
  2. Semaglutide (Wegovy): Average weight loss of 15-17%
  3. Liraglutide (Saxenda): Average weight loss of 5-7%

A graphic displaying the top three best weight loss injections in the UK in 2024 based on weight loss outcomes.

You can purchase both Wegovy and Mounjaro as part of Second Nature’s Wegovy weight-loss programme and our Mounjaro weight-loss programme.

So, what are the best injectables for weight loss? Read on as we review Mounjaro, Wegovy, and Saxenda.

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1) Tirzepatide (Mounjaro)

The best weight-loss injection that’s available in the UK in 2024 is tirzepatide, sold under the brand names Mounjaro.

Tirzepatide has been approved in the UK for weight loss and type 2 diabetes. It’s currently available to purchase privately for weight loss, assuming you meet the eligibility criteria.

Research has shown that tirzepatide supports an average weight loss of around 25% after one year. This study also showed this weight loss was maintained after 20 months on the medication.

Tirzepatide is a weight-loss injection that you administer once a week and is manufactured by the pharmaceutical company Eli Lilly.

2) Semaglutide (Wegovy and Ozempic)

The second-best weight-loss injection available in the UK in 2024 is semaglutide 2.4 mg (Wegovy).

Research has shown that semaglutide 2.4 mg (Wegovy) can support weight loss of around 16% after one year.

Wegovy has the same active ingredient as the type 2 diabetes medication Ozempic. Ozempic is available in doses up to 1 mg but is no longer available for weight loss in the UK.

Semaglutide is a weight-loss injection that you administer once weekly and is manufactured by the pharmaceutical company Novo Nordisk.

Second Nature launched a Wegovy weight-loss programme in 2023.

3) Liraglutide (Saxenda)

The third-best weight-loss injection available in the UK in 2024 is liraglutide (Saxenda). Research shows that liraglutide supports average weight loss of 5-7% after one year.

Saxenda is also prescribed for people living with type 2 diabetes, and while its impact on weight loss is modest, Saxenda has a very positive impact on blood sugar control.

One study showed that Saxenda supported over 56% of participants in lowering their blood sugars below the diagnostic threshold for type 2 diabetes.

Liraglutide is a weight-loss injection administered once daily and manufactured by the pharmaceutical company Novo Nordisk.

Weight-loss injections aren’t a magic pill

Weight-loss injections are designed as additional tools for weight management interventions and shouldn’t be considered lifelong medications.

Instead, they should be used to help you kickstart your weight loss and healthy journey while you commit to living a healthier lifestyle.

Consider the use of antidepressants for people living with depression. They’re not designed to cure the condition. Instead, they’re designed to allow room for therapy to treat the condition’s underlying cause.

Mounjaro, and other weight loss injections, like Ozempic and Wegovy, are similar. They can allow you to make lifestyle changes to support long-term weight loss maintenance.

Mounjaro can help silence food-related thoughts and also give you a boost of confidence with more immediate weight-loss results.

This helps to buy you the time and headspace to understand why your body may have struggled to lose weight previously, and to build new long-term healthy habits.

The core focus of our medication programmes is to calm down the feeling of food noise, lower your cravings, and allow you to build healthier habits to keep the weight off for good.

The ultimate goal is to make losing weight feel second nature.

Second Nature’s medication-supported programmes

Second Nature has two medication-supported programmes: a Wegovy weight-loss programme and our Mounjaro weight-loss programme.

If you’ve made the decision to try Wegovy or Mounjaro (assuming you’re eligible), why should you choose Second Nature over other medication providers?

For peace of mind.

Second Nature has worked with the NHS for over 6 years providing weight-loss programmes across the UK.

Whilst our Wegovy and Mounjaro weight-loss programmes are private and not currently used by the NHS, we’ve built the programmes with a focus on scientific evidence, patient safety, and data security.

We hope that our 6+ years of working with the NHS and building a track record of effective weight-loss results will give you peace of mind to give us a try.

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