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GLP-1s

How much does Mounjaro cost in the UK?

Robbie Puddick
Written by

Robbie Puddick

Medically reviewed by

Fiona Moncrieff

4 min read
Last updated February 2024
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Jump to: What is Mounjaro? | How do you get a prescription for Mounjaro? | Can I get Mounjaro over the counter? | Does Mounjaro have side effects?

A private prescription of Mounjaro will start from £229 a month with Second Nature’s Mounjaro weight-loss programme.

This will include access to our award-winning weight-loss programme alongside the 1-1 support of a registered nutritionist or dietitian.

Mounjaro will be available to buy online from Second Nature at the end of February 2024. To sign up for our waiting list and be emailed as soon as Mounjaro is launched, you can visit our waiting list form.

Check my eligibility

What is Mounjaro?

Mounjaro is a dual-function medication for individuals living with type 2 diabetes and obesity. Its active ingredient is tirzepatide.

Tirzepatide is sold under the brand name Mounjaro in the UK, or Zepbound for obesity in the U.S., and manufactured by the pharmaceutical company Eli Lily.

Tirzepatide mimics two hormones in the body: GLP-1 and glucose-dependent insulinotropic polypeptide (GIP).

When we eat food, our gut releases a hormone that helps the body regulate hunger and blood sugar levels. This hormone is called GLP-1 (glucagon-like peptide-1).

The actions of GLP-1 are the target of Mounjaro and other medications like Wegovy, Saxenda, and Ozempic.

This class of medications are known as GLP-1 receptor activators (GLP-1s). They mimic the actions of the hormone GLP-1 to activate the GLP-1 receptors.

GLP-1s improve insulin function to lower blood sugar levels and delay gastric emptying, decreasing appetite. GLP-1s also communicate with the brain’s appetite control centre, the hypothalamus, to reduce food-seeking behaviour.

Separately to GLP-1s, the other hormone that Mounjaro mimics is called GIP.

GIP is a hormone released in response to food that helps regulate blood sugar levels and helps our fat cells ‘absorb’ more excess energy, preventing fat from being stored in the liver or pancreas.

GIP also has receptors in the brain, similar to GLP-1, and scientists believe it’s also involved in regulating appetite.

The medications that mimic GIP are known as GIP mimetics. These additional actions are the target of Mounjaro.

So, tirzepatide has a dual function that mimics two hormones in the body that support blood glucose levels and weight loss.

How do you get a prescription for Mounjaro?

For Second Nature’s Mounjaro programme, you’ll qualify for Mounjaro if you have a BMI of over 27 and also meet other eligibility criteria.

However, we’re unable to share this information online, and you must complete our health quiz first for us to check your eligibility.

If you’re living with type-2 diabetes, to receive a Mounjaro (tirzepatide) prescription via the NHS in the UK, here are the eligibility criteria confirmed by NICE:

  • Triple therapy with metformin and two other oral antidiabetic drugs is ineffective, not tolerated or contraindicated, and
  • they have a body mass index (BMI) of 35 kg/m2 or more and specific psychological or other medical problems associated with obesity,
  • or they have a BMI of less than 35 kg/m2, and:
    • insulin therapy would have significant occupational implications, or
    • weight loss would benefit other significant obesity-related complications.

Lower BMI thresholds (usually reduced by 2.5 kg/m2) apply for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean family backgrounds.

Can I get Mounjaro over the counter?

Mounjaro will not be available over the counter in the UK; it will only be available with a prescription.

Does Mounjaro have side effects?

All medications have potential side effects, and Mounjaro is no different. The most common side effects of Mounjaro are nausea, constipation, vomiting, and other symptoms affecting the gastrointestinal (GI) tract, like diarrhoea.

You might also experience less common side effects like tiredness or headaches.

These symptoms most commonly occur around the time of the injection, during dose escalation, and are typically transient and will ease after you’ve adapted to the medication.

However, everyone responds differently to these medications; some people won’t experience any side effects, while others will have to discontinue their medication due to the discomfort the side effects cause.

Not a magic pill

Weight-loss injections are designed as additional tools for weight management interventions and shouldn’t be considered lifelong medications.

Instead, they should be used to help you kickstart your weight loss and healthy journey while you commit to living a healthier lifestyle.

Consider the use of antidepressants for people living with depression. They’re not designed to cure the condition. Instead, they’re designed to allow room for therapy to treat the condition’s underlying cause.

Mounjaro, and other weight loss injections, like Ozempic and Wegovy, are similar. They can allow you to make lifestyle changes to support long-term weight loss maintenance.

Second Nature’s medication-supported programmes

Second Nature has two medication-supported programmes: a Wegovy weight-loss programme and a Mounjaro weight-loss programme.

If you’ve made the decision to try Wegovy or Mounjaro (assuming you’re eligible), why should you choose Second Nature over other medication providers?

For peace of mind.

Second Nature has worked with the NHS for over 6 years providing weight-loss programmes across the UK.

Whilst our Wegovy and Mounjaro weight-loss programmes are private and not currently used by the NHS, we’ve applied the same high standards of scientific evidence, patient safety, and data security, as those required by our NHS partnerships.

We hope that our 6+ years of working will the NHS and building a track record of trust and effective weight-loss results will give you peace of mind to give us a try.

As a reminder, to sign up for our waiting list and be emailed as soon as Mounjaro is launched, you can visit our waiting list form.

Check my eligibility

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