Jump to: Key differences | Clinical credibility & expertise | Programme structure & support | Pricing & value comparison | Long-term outcomes | Take home message
When choosing between Cloud Pharmacy and Second Nature for weight loss medication, the fundamental difference is the level of support you receive alongside the medication.
Second Nature combines Mounjaro with support from registered dietitians and nutritionists, building on six years of NHS partnership and proven clinical outcomes.
Cloud Pharmacy focuses on providing medications at the most competitive prices online, positioning itself as the budget option with basic pharmacy oversight but minimal behavioural support.
Both services provide access to effective weight-loss medications, but the level of professional support, habit-change guidance, and post-medication planning differs dramatically.
The choice comes down to whether you want the cheapest medication access or comprehensive support for building sustainable habits alongside your treatment.
Key differences between Cloud Pharmacy and Second Nature
| Feature |
Second Nature |
Cloud Pharmacy |
| Core Approach |
Comprehensive habit formation alongside medication |
Lowest-price medication provision with basic monitoring |
| NHS Partnership |
NHS-commissioned since 2017, used by over half of UK Health Boards |
Licensed pharmacy, no NHS programmes |
| Clinical Evidence |
Multiple peer-reviewed publications with proven outcomes |
References medication trial data only |
| Health Support |
UK-registered dietitians and nutritionists with GLP-1 expertise |
Basic pharmacist follow-ups and advice |
| Digital Tools |
Custom app with tracking, recipes, and education |
Basic online consultation platform |
| Monthly Cost |
£229-£299 (all-inclusive with £100 off first month) |
£158.99-£191.99 Mounjaro, £159-£259 Wegovy |
| Post-medication Planning |
Comprehensive transition strategies and ongoing support |
Basic guidance for maintenance phase |
| Value Proposition |
Complete programme for sustainable weight loss |
Cheapest medication prices online |
| Trustpilot Rating |
4.6/5 from 7,600+ reviews |
4.7/5 from 7,500+ reviews |
Clinical credibility & expertise
The level of clinical backing and professional support represents the biggest difference between these services.
Second Nature: NHS-validated comprehensive approach
Since 2017, the NHS has chosen Second Nature to deliver weight loss and type 2 diabetes programmes across the UK.
Over half of all UK NHS Health and Care boards now use our services, demonstrating healthcare professionals’ confidence in our evidence-based approach.
Our clinical effectiveness is supported by research published in the British Medical Journal, showing participants lose an average of 5.9kg at 12 weeks with 62.5% achieving clinically meaningful weight loss.
Recent research on our medication programme, published in JMIR Formative Research, demonstrated participants lost an average of 6.5kg (6.4% body weight) after 3 months on our Mounjaro programme.
Our team includes UK-registered dietitians and nutritionists who specialise in supporting people taking weight-loss medications, with specific training in side effect management and habit formation.
Cloud Pharmacy: basic medication provision
Cloud Pharmacy operates as a registered online pharmacy, providing medication access with basic pharmacist oversight and follow-up consultations.
Founded by pharmacists Ibrahim and Nazmul, the service focuses on making weight-loss medications accessible at competitive prices with straightforward online consultations.
For effectiveness claims, Cloud Pharmacy references medication clinical trials (such as Mounjaro’s 15-20% weight loss potential) rather than programme-specific outcomes data.
While they provide qualified pharmacist support, this focuses on medication management rather than the comprehensive nutritional and behavioural guidance that registered dietitians offer.
Programme structure & support
The daily experience and level of guidance differs substantially between these approaches.
Second Nature: comprehensive habit-change programme
Our programme is designed around building sustainable habits that work alongside medication, delivered through multiple support channels.
You get access to UK-registered dietitians and nutritionists five days a week via both group and private chat.
These professionals have specific expertise in supporting people taking weight-loss medications, understanding both how to improve eating habits and side effect management.
Our custom app includes over 300 recipes designed for people taking weight-loss medications, habit-tracking tools, educational content, and progress monitoring. You’re placed in small peer support groups, creating community and accountability.
The programme prepares you for life after medication from day one, focusing on building habits that maintain your progress long-term. This includes meal planning skills, social eating strategies, and developing a healthy relationship with food.
Cloud Pharmacy: medication-focused with basic support
Cloud Pharmacy provides straightforward medication access through online consultations followed by direct delivery to your door.
Their service includes basic pharmacist follow-ups to monitor progress and adjust dosing as needed. They offer practical elements like advice on injection techniques and general guidance on combining medication with diet and exercise.
The approach assumes you can independently manage the lifestyle changes needed for weight loss, providing medication as the primary intervention with minimal structured behavioural support.
For patients reaching maintenance phase, they offer basic guidance on dose adjustments and long-term medication planning, but don’t provide structured habit-formation support.
Pricing & value comparison
Understanding the full cost and what’s included helps evaluate the true value of each approach.
Pricing breakdown
Second Nature:
- Monthly cost: £229-£299 (increases with higher doses)
- First month discount: £100 off
- Includes: Medication, delivery, app access, dietitian support, peer groups, educational content, habit-building tools
Cloud Pharmacy:
- Mounjaro: £158.99-£191.99 monthly (increases with higher doses)
- Wegovy: £159-£259 monthly (increases with higher doses)
- Includes: Medication, delivery, basic pharmacist follow-ups
Value analysis
Cloud Pharmacy’s medication-only pricing is significantly lower, reflecting their focus on cost competition rather than comprehensive support.
The £70-140 monthly difference represents the cost of professional dietitian support, structured education, peer community, and post-medication planning that Second Nature provides.
Cloud Pharmacy works well if you’re confident managing dietary and lifestyle changes independently and primarily need affordable medication access.
Second Nature’s higher cost reflects comprehensive support for building sustainable habits, which research shows is crucial for maintaining weight loss after stopping medication.
Long-term outcomes
The real test is maintaining results and building healthier relationships with food that last beyond medication use.
Second Nature: building for lasting success
Our approach focuses on sustainable weight maintenance through habit formation and skill development. Our NHS research shows 6.2kg average weight loss at 12 months, with many participants maintaining results beyond the programme period.
We recognise medication provides a window to build healthier patterns, but lasting success requires addressing the psychological and environmental factors that influenced weight gain originally.
Our programme teaches practical skills like meal planning, social eating navigation, and stress management without relying on food. These capabilities support weight maintenance long after medication ends.
User satisfaction reflects this comprehensive approach, with 4.6/5 stars from over 7,600 Trustpilot reviews, many highlighting lasting habit changes developed during the programme.
Cloud Pharmacy: medication-focused approach
Cloud Pharmacy’s outcomes focus on medication effectiveness, referencing clinical trials showing 15-20% weight loss potential with Mounjaro and similar results with Wegovy.
Their approach expects individuals to independently develop lifestyle strategies for maintaining weight loss after stopping medication, with basic pharmacist guidance during the maintenance phase.
Success depends largely on personal motivation and self-directed habit change, as the service doesn’t include structured behavioural support for building long-term weight management skills.
Patient reviews highlight satisfaction with medication access and pricing, with 4.7/5 stars from 7,500+ reviews focused primarily on service delivery rather than long-term outcomes.
Take home message
Weight-loss medications can be transformative when used appropriately, but the level of support you receive significantly impacts long-term success.
Choose Second Nature if you value:
- NHS-backed comprehensive support: Partnership and published research providing confidence in approach
- Professional guidance: UK-registered dietitians with extensive weight-loss medication expertise
- Sustainable habit formation: Learning skills that last beyond medication use
- Community support: Peer groups and ongoing professional guidance
- Post-medication planning: Comprehensive strategies for maintaining results long-term
- Proven track record: Six years of NHS collaboration with established outcomes
Choose Cloud Pharmacy if you value:
- Lowest prices: Most competitive medication costs online with price matching
- Straightforward access: Quick consultations with fast medication delivery
- Self-directed approach: Confidence in managing lifestyle changes independently
- Basic medical oversight: Pharmacist support without extensive programme structure
- Cost efficiency: Focusing budget on medication rather than comprehensive support
The key question is whether you want the cheapest medication access or comprehensive support for building habits that last beyond medication use.
At Second Nature, we believe sustainable weight management requires more than medication alone. Our programme teaches you to build a healthier relationship with food through understanding habits, not just relying on medication effects.
If you’re confident managing lifestyle changes independently and primarily need affordable medication access, Cloud Pharmacy offers competitive pricing with basic professional oversight.
If you want comprehensive support for building sustainable habits that work long after medication ends, our NHS-validated approach provides the foundation for lasting transformation.
Remember that successful weight management is about creating sustainable changes that support your health for years to come, not just achieving short-term weight loss.
Second Nature's Mounjaro programme
Second Nature provides Mounjaro as part of our Mounjaro weight-loss programme
Why choose Second Nature over other medication providers, assuming you’re eligible?
Because peace of mind matters.
We’ve had the privilege of working with the NHS for over eight years, helping people across the UK take meaningful steps toward a healthier, happier life.
Our programmes are designed to meet people where they are, whether that means support with weight loss through compassionate one-to-one health coaching, or access to the latest weight-loss medications (like Mounjaro) delivered alongside expert care from a multidisciplinary team of doctors, psychologists, dietitians, and personal trainers.
At the heart of everything we do is a simple belief: real, lasting change comes from building better habits, not relying on quick fixes. We’re here to support that change every step of the way.
With over a decade of experience, thousands of lives changed, and a long-standing record of delivering programmes used by the NHS, we believe we're the UK’s most trusted weight-loss programme.
We hope to offer you something invaluable: peace of mind, and the support you need to take that first step.
