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How much weight can you lose in a month on Ozempic?

Robbie Puddick
Written by

Robbie Puddick

Medically reviewed by

Fiona Moncrieff

4 min read
Last updated June 2024

Jump to: How much weight will I lose on Ozempic? | Do you lose more weight on the higher doses of Ozempic? | Ozempic is no longer available as a weight-loss injection in the UK

According to data from randomised controlled trials, Ozempic supports weight loss of around 1kg or around 1.1% of body weight after one month. After two months, it’s around 2kg or 2.2% of body weight.

A graphic showing how much weight you lose in the first month on Ozempic. It also shows how much weight you lose after two months on Ozempic.

Interestingly, this initial weight loss is no different to other weight loss treatments or the impact of diet interventions on weight loss. The real effect of semaglutide is seen beyond three months.

It’s worth noting that Ozempic is no longer available to purchase for weight loss in the UK.

The two most popular alternatives are Wegovy and Mounjaro, which are both available in the UK for weight loss.

Wegovy is the same medication as Ozempic (the drug is called ‘semaglutide’), but it’s available in higher doses and it’s also specifically approved for weight loss.

Mounjaro (the drug is called ‘tirzepatide’) is the brand new weight-loss medication from the pharmaceutical company, Eli Lilly. It was launched in February 2024 and clinical trials have suggested better long-term weight-loss results than both Wegovy and Ozempic.

Second Nature has both a Wegovy weight-loss programme and a Mounjaro weight-loss programme. Both programmes start from £229 per month, and to see if you’re eligible you need to take our short health quiz.

Check my eligibility

How much weight will I lose on Ozempic?

Semaglutide reduces appetite and hunger, helping you eat fewer calories; this effect is almost immediate.

Semaglutide is a long-acting medication that’s started at a lower dose to reduce the number and severity of side effects as it’s built up to a higher maintenance dose.

Research suggests that Ozempic supports average weight loss of around 6kg after 40 weeks. However, as this is an average, it’s unclear how much weight each individual will be able to lose on Ozempic.

The amount of weight people lose on Ozempic will depend on how well they respond to the medication and their ability to make positive changes to their diet and lifestyle.

Do you lose more weight on the higher doses of Ozempic?

Research suggests that higher doses of Ozempic support more weight loss. One study showed that after 30 weeks, 1 mg of Ozempic led to a weight loss of 4.5kg, compared to 3.7kg with Ozempic 0.5 mg.

A graph showing the difference in weight loss between 0.5 mg and 1 mg of Ozempic

However, as we’ve discussed already, everyone responds differently to medication and how much weight you lose will depend on how well you respond to the medication and the changes you’re able to make to your lifestyle.

For example, some people may lose more weight on the lower doses of Ozempic as they’re more sensitive to the drug’s effects and don’t need to increase the dosage.

Ozempic is no longer available as a weight-loss injection in the UK

Under new government regulations, healthcare providers can no longer prescribe Ozempic to patients for weight loss. It’s only approved for people living with type 2 diabetes.

However, both Wegovy and Mounjaro are available in the UK for weight loss, and research suggests that both weight-loss drugs lead to more weight loss than Ozempic.

Ozempic isn’t a magic pill

Weight-loss injections are designed as additional tools for healthy lifestyle change and shouldn’t be considered as lifelong medications.

Instead, they should be used to help you kickstart your weight-loss journey whilst you focus on building new, healthy habits.

Consider the use of antidepressants for people living with depression. They’re not designed to cure the condition. Instead, they’re designed to allow room for therapy to treat the condition’s underlying cause.

Mounjaro and Wegovy are similar. These medications can help silence food-related thoughts and also give you a boost of confidence with more immediate weight-loss results.

This helps to buy you the time and headspace to understand why your body may have struggled to lose weight previously, and to build new long-term healthy habits.

The core focus of our medication programmes are to calm down the feeling of food noise, lower your cravings, and to allow you to build healthier habits to keep the weight off for good.

The ultimate goal is to make losing weight feel second nature.

Second Nature’s medication-supported programmes

Second Nature has two medication-supported programmes: a Wegovy weight-loss programme and a Mounjaro weight-loss programme.

If you’ve made the decision to try Wegovy or Mounjaro (assuming you’re eligible), why should you choose Second Nature over other medication providers?

For peace of mind.

Second Nature has worked with the NHS for over 6 years providing weight-loss programmes across the UK.

Whilst our Wegovy and Mounjaro weight-loss programmes are private and not currently used by the NHS, we’ve built the programmes with a focus on scientific evidence, patient safety, and data security.

We hope that our 6+ years of working with the NHS and building a track record of effective weight-loss results will give you peace of mind to give us a try.

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Write a response

Ivory Davis

24 February, 2024

Do you send me the medication or do I have to pay or you send me a prescription and I go pay at the pharmacy?

Robbie Puddick

26 February, 2024

Hi Ivory,

You’ll need to check your eligibility for our medication programmes, you need to complete our online consultation.


Linda Herrington

8 February, 2024

Need to know more

Ronda lowman

30 January, 2024

I love ozempic I don’t get sick, nausea,I don’t have problems with my pancreas on this.iv had pancreatitis with most others so it’s helping control my diabetes I don’t know how much weight if any IV lost I’m really interested for my diabetes


5 February, 2024

I also take Ozempic do you take 0.5
I like it it really has helped my a1c.

Nicole lalande

26 January, 2024

I live in Quebec how can I find out if I could be available for this medication? I’m 75 years of age take other medicine for high blood pressure and for my thyroid. I now have lymphocytic colitis was diagnosed last year with a colonoscopy test . Would Like some respond to my situation.

Angela Anderson

18 January, 2024

I would like to know more about the medication

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