Second Nature logo



What is the newest weight-loss injection in the UK?

Robbie Puddick
Written by

Robbie Puddick

Medically reviewed by

Fiona Moncrieff

2 min read
Last updated February 2024

Jump to: What’s the most effective weight-loss injection? | Can you get weight-loss injections on the NHS? | Weight-loss injections aren’t a magic pill

The newest weight-loss injection to be approved in the UK is tirzepatide, sold under the brand name Mounjaro.

Tirzepatide was approved in the UK for weight loss in November 2023 after it was approved for people living with type 2 diabetes in September 2023.

Tirzepatide’s well-known brand name is Mounjaro, and it’s currently available in the U.S. for type 2 diabetes.

Mounjaro will launch in the UK in February or March 2024, and Second Nature will launch a Mounjaro weight-loss programme.

Other weight-loss injections available in the UK are semaglutide (Wegovy) and liraglutide (Saxenda).

Take our quiz

What’s the best weight-loss injection in the UK?

Based on data from randomised controlled trials, tirzepatide appears to be the most effective weight-loss injection and tends to support more weight loss than Wegovy or Saxenda.

Tirzepatide supports average weight loss of around 25% after one year, compared to 17% on Wegovy and 7% on Saxenda.

However, everyone responds differently to medications, and it’ll be down to the individual and their healthcare team to determine the best course of treatment for them.

Can you get weight-loss injections on the NHS?

Wegovy and Saxenda are currently available via prescription on the NHS. However, these are only available alongside participation in a specialist weight management programme which has strict criteria for entry.

We recommend speaking with your GP or local healthcare team to discuss the weight management solutions available in your area.

Weight-loss injections aren’t a magic pill

Weight loss injections are designed as additional tools for weight management interventions and shouldn’t be considered lifelong medications.

Instead, they should be used to help you kickstart your weight loss and healthy journey while you commit to living a healthier lifestyle.

Consider the use of antidepressants for people living with depression. They’re not designed to cure the condition. Instead, they’re designed to allow room for therapy to treat the condition’s underlying cause.

Mounjaro and other weight loss injections, like Saxenda and Wegovy, are similar. They can allow you to make lifestyle changes to support long-term weight loss maintenance.

At Second Nature, we’ve been trusted by the NHS since 2017 to support people with type 2 diabetes and obesity to lose weight, manage their blood sugar levels, and lead healthier lifestyles for the long term.

Ideally, we’d lose weight without medication, and we’d recommend trying our weight-loss programme before trying a weight-loss injection, as it’s cheaper and potentially more sustainable in the long term.

In 2022, the NHS published data in the BMJ that compared the weight loss outcomes of five providers in the National Diabetes Prevention Programme.

Second Nature was more than twice as effective at supporting weight loss than the other four providers.

So, if you’ve decided you want to try a weight-loss jab with the support of the Second Nature programme, click on the button below.

Take our quiz

You might also like

Make losing weight feel Second Nature

The first step on your Second Nature journey is to take our health quiz.

Hand holding phone

Write a response

As seen on

The GuardianThe TimesChannel 4The Sunday Telegraph
Evening Standard