At-a-glance comparison
| Feature |
Second Nature |
Well Pharmacy |
| Core approach |
Medication + comprehensive habit change programme |
Medication + monthly pharmacist check-ins |
| Professional support |
Daily access to registered dietitians/nutritionists |
Monthly clinical reviews with pharmacists |
| Support format |
Digital coaching via app with group support |
Video consultations and in-branch appointments |
| Wegovy pricing (2025) |
£149-£249 monthly (£50 off first month) for Wegovy |
£127-£250 monthly depending on dose |
| UK locations |
Digital-first nationwide programme |
700+ physical branches plus online service |
| NHS partnership |
NHS-commissioned since 2017, supports 250,000+ patients |
No NHS partnerships |
| Customer satisfaction |
4.6/5 on Trustpilot (7,600+ reviews) |
4.3/5 on Trustpilot (31,000+ reviews) |
| Medication options |
Wegovy and Mounjaro |
Wegovy, Mounjaro, and other weight-loss medications like Saxenda |
Service structure comparison
Well Pharmacy has enhanced its weight loss services in 2025, evolving beyond basic prescription delivery to include structured clinical support.
Their weight management service now includes:
- Initial BMI assessment and eligibility check
- Monthly clinical review appointments (video or in-person)
- Ongoing check-ins for side effect management
- Dose adjustment consultations
- Basic lifestyle advice
- Access to 700+ UK branches for face-to-face support
While this represents a substantial improvement over medication-only services, it’s important to understand how it differs from Second Nature’s approach.
Second Nature provides:
- Daily access to registered dietitians/nutritionists (five days a week)
- Psychology-based habit formation programme
- Small group support with peers on similar journeys
- Structured educational content and practical tools
- Custom-built app with tracking features
- Regular progress reviews and personalised guidance
The fundamental difference is in frequency and depth of support. Well Pharmacy’s monthly check-ins focus primarily on clinical oversight, while Second Nature’s daily access addresses the psychological and behavioural aspects of weight management.
Support and professional guidance
When taking Wegovy, the type and frequency of support can significantly impact both your experience and long-term results.
Well Pharmacy’s clinical support
Well Pharmacy provides pharmacist-led clinical oversight that focuses on:
- Medication safety monitoring
- Side effect management
- Dose adjustments when needed
- General health guidance
- Prescription renewals
- Answering medication-related questions
This approach ensures you receive professional medical supervision throughout your treatment but places responsibility for daily decision-making and habit changes largely on you.
Second Nature’s comprehensive approach
Second Nature combines clinical oversight with daily behavioural support that includes:
- Guidance from registered dietitians/nutritionists available five days a week
- Personalised advice for managing side effects through food choices
- Strategies for navigating social situations while on medication
- Psychological techniques for changing long-term eating patterns
- Community support from others experiencing similar challenges
- Practical tools for building sustainable habits
Leading behavioural research shows that consistent and frequent support – rather than infrequent or isolated contacts – is crucial for maintaining healthy habits and improving long-term weight management results.
Programmes with more support (such as weekly or more regular coach or peer contact, frequent self-monitoring, and ongoing feedback) are associated with greater adherence to healthy behaviours, as well as higher rates of clinically meaningful weight loss and maintenance compared to less frequent or minimal follow-up.
2025 price analysis
Recent industry-wide price changes have affected all UK Wegovy and Mounjaro providers, making it essential to understand current costs.
Wegovy pricing comparison
| Dose |
Well Pharmacy |
Second Nature |
| Starting dose |
£127/month |
£149/month (£99 first month) |
| 1.7mg |
~£200/month |
£199/month |
| 2.4mg |
~£250/month |
£249/month |
| First 3 months |
~£527 |
£447 (with first month discount) |
| 6-month total |
~£1,277 |
£1,244 (with first month discount) |
Note: Well Pharmacy prices are approximate based on current published ranges. Exact pricing may vary.
The pricing appears comparable at first glance, with Well Pharmacy slightly less expensive for the starting dose but similar for maintenance doses.
However, when factoring in Second Nature’s first month discount, the total costs over 3-6 months become very similar.
The value equation
When considering value rather than just price, important factors include:
- Support frequency (daily vs monthly)
- Professional expertise (dietitians/nutritionists vs pharmacists)
- Long-term habit development
- Post-medication transition planning
Weight regain research
The scientific evidence on weight maintenance after stopping GLP-1 medications highlights the importance of developing sustainable habits during treatment.
Post-medication weight trends
A study tracked participants after they stopped semaglutide (Wegovy) and showed:
- Average weight loss after 68 weeks on medication: 17.3%
- Average weight after 52 weeks post-medication: 5.6% below baseline
- Weight regained: 11.6% (67% of lost weight)
This research demonstrates that without addressing underlying habits, significant weight regain is common after stopping medication.
The importance of support
Research published in Practical Diabetes by Second Nature demonstrates that engagement level significantly impacts weight loss outcomes.
Our study found that participants with high engagement levels with all aspects of the application achieved 9.5kg weight loss after 12 months compared to low engagers who achieved 6.7kg, a 42% difference.
As shown in the research, support interactions had the strongest connection with weight loss success. Participants with high support engagement achieved 9.3kg weight loss compared to just 5.8kg for those with low support engagement, a 60% difference.
Second Nature’s preliminary data suggests participants who develop sustainable habits while on medication maintain significantly better weight control after stopping, with only 3.2% weight regain at five months compared to the typical 11-14% seen in clinical studies.
Customer experience
Both providers receive positive reviews overall, but customer feedback highlights different strengths and limitations.
Well Pharmacy feedback
Recent Trustpilot reviews for Well Pharmacy (4.3/5 stars across 31,000+ reviews) highlight:
Strengths:
- Fast medication delivery
- Professional in-branch staff
- Convenience of physical locations
- Straightforward online ordering
- Flexibility of video or in-person consultations
Limitations:
- Occasional difficulty reaching support staff
- Communication delays during busy periods
- Variable experience depending on local branch
- Limited out-of-hours support
Second Nature feedback
Second Nature maintains a 4.6/5 Trustpilot rating across 7,600+ reviews, with consistent positive feedback about:
Strengths:
- Responsive support from health coaches
- Depth of nutritional guidance
- Supportive peer community
- Practical strategies for habit change
- Comprehensive educational content
Limitations:
- Digital-only approach (no physical locations)
- Learning curve for app features
- Group support format not ideal for everyone
This comprehensive approach is reflected in member testimonials. As one Second Nature participant shared:
“Having carried out lots of research, I opted to do my medicated weight loss program with Second Nature. Each day there is information to listen to or read (whichever is your preference) to educate you on food, eating right, being healthy … to retrain and learn how to make the right choices once a healthy weight is reached.
The support of my coach Monet has been so useful, in motivating me to eat enough protein, to exercise, to query my past and present food choices.
These support mechanisms, the medication itself, and the support of my group (sharing our experiences on the journey) are empowering me to know that this time my yo-yo dieting past is behind me and a healthier me is already emerging. Thank you Second Nature!”
This firsthand experience highlights how the combination of daily education, coach support, and group community creates a framework for sustainable change beyond medication alone.
NHS partnership
Second Nature’s NHS partnerships and six-year history of delivering NHS-commissioned services demonstrate a commitment to high clinical standards and evidence-based practice.
Since 2017, Second Nature has:
- Supported over 250,000 NHS patients
- Been commissioned by more than two-thirds of UK NHS Health and Care boards
- Published peer-reviewed research on programme outcomes
- Received NICE approval for digital weight management
The National Institute for Health and Care Excellence (NICE) announcement that Wegovy would be available via digital weight management services provided by Second Nature and three other companies supporting the NHS recognises the high level of patient care and professional standards.
While Well Pharmacy is a respected UK pharmacy chain, it does not currently deliver NHS-commissioned weight management programmes, which means its weight loss services haven’t undergone the same level of NHS evaluation and approval.
Who should choose each option?
Consider Second Nature if you:
- Value daily expert support rather than monthly check-ins
- Want guidance from registered dietitians/nutritionists
- Benefit from community and peer accountability
- Are concerned about maintaining results after medication
- Have struggled with emotional eating
- Prefer a digital-first approach with app-based tools
- Value programmes with NHS validation
Consider Well Pharmacy if you:
- Prefer face-to-face interactions at physical locations
- Value the convenience of in-branch appointments
- Feel monthly clinical check-ins provide sufficient support
- Are confident in your self-management abilities
- Have strong existing nutrition knowledge
- Benefit from direct pharmacist consultations
- Want the option of both online and in-person service
Frequently asked questions
How often will I meet with a healthcare professional with each provider?
With Second Nature, you’ll have daily access to a registered dietitian or nutritionist five days a week through the app, plus regular check-ins about your medication.
With Well Pharmacy, you’ll have monthly scheduled appointments with a pharmacist, either by video or in-person at one of their 700+ branches.
What happens if I experience side effects?
Well Pharmacy provides pharmacist consultations for side effect management, with the ability to book appointments when needed.
Second Nature offers immediate support through dietitians who can provide specific food strategies to manage nausea and other common side effects, plus access to a supportive community who can share their experiences.
Will I keep the weight off after stopping medication?
Research shows 67% of weight is typically regained after stopping Wegovy without adequate habit change. Second Nature’s daily support and comprehensive behaviour change programme is specifically designed to develop the habits needed for long-term maintenance, with preliminary data showing significantly less weight regain.
Well Pharmacy provides clinical monitoring but less intensive behavioural support, which may impact long-term outcomes.
How do I know which option is right for me?
Consider your past weight loss attempts and what support you’ve found most helpful. If you’ve struggled with emotional eating or found it difficult to maintain weight loss in the past, Second Nature’s comprehensive approach may be beneficial.
If you’re highly self-motivated and primarily need clinical oversight, Well Pharmacy may be fine for you.
Can I switch providers if I’m not satisfied?
Yes, you can request your prescription records from either provider and transfer to another service. However, be aware that there will be a new consultation process with the new provider.
Take home message
Both Second Nature and Well Pharmacy offer legitimate ways to access Wegovy or Mounjaro in the UK, but with fundamentally different approaches to supporting your weight loss journey.
Well Pharmacy provides monthly pharmacist check-ins with the convenience of 700+ physical locations, making it suitable for those who value face-to-face interactions and feel confident managing day-to-day decisions independently.
Second Nature combines medication with daily access to registered dietitians, a psychology-based habit change programme, and peer support, offering a more comprehensive approach for those concerned about long-term results and post-medication maintenance.
Recent research indicates that support frequency significantly impacts outcomes, particularly after stopping medication, with daily guidance showing better long-term weight maintenance than monthly check-ins alone.
Your choice should ultimately reflect your personal needs, past experiences with weight management, and the level of support you believe will help you develop sustainable habits for lasting results.
Second Nature's Mounjaro and Wegovy programmes
Second Nature provides Mounjaro or Wegovy as part of our Mounjaro and Wegovy weight-loss programmes.
Why choose Second Nature over other medication providers, assuming you're eligible?
Because peace of mind matters.
We've had the privilege of working with the NHS for over eight years, helping people across the UK take meaningful steps toward a healthier, happier life.
Our programmes are designed to meet people where they are, whether that means support with weight loss through compassionate one-to-one health coaching, or access to the latest weight-loss medications (like Mounjaro and Wegovy) delivered alongside expert care from a multidisciplinary team of doctors, psychologists, dietitians, and personal trainers.
At the heart of everything we do is a simple belief: real, lasting change comes from building better habits, not relying on quick fixes. We're here to support that change every step of the way.
With over a decade of experience, thousands of lives changed, and a long-standing record of delivering programmes used by the NHS, we believe we're the UK's most trusted weight-loss programme.
We hope to offer you something invaluable: peace of mind, and the support you need to take that first step.
