Second Nature logo



Can you switch from Ozempic to Wegovy?

Robbie Puddick
Written by

Robbie Puddick

Medically reviewed by

Fiona Moncrieff

2 min read
Last updated June 2024

Jump to: Do you lose more weight on Ozempic or Wegovy? | How to switch to Wegovy on Second Nature

If the clinical team approves you, you can switch from Ozempic to Wegovy on Second Nature via our Wegovy-supported programme.

Semaglutide, the active ingredient in Ozempic and Wegovy, is a medication approved for type 2 diabetes and obesity treatment in the UK.

Despite Ozempic and Wegovy containing the same active ingredient, they aren’t interchangeable, which means they can’t be used at the same time.

However, it’s worth noting that if you were on Ozempic 0.5 mg or 1 mg, you’d need to drop down to Wegovy 0.25 mg to continue your treatment on semaglutide with Second Nature.

This drop in dosing is due to Wegovy’s strict treatment protocol on Second Nature.

Wegovy is approved for weight loss in the UK, and its dosing schedule starts at 0.25 mg and rises to 2.4 mg incrementally after five months.

Many people have moved to Second Nature’s Wegovy-supported programme after being on Ozempic with other providers and found that it can be challenging to drop back down to 0.25 mg after being on a higher dose.

Still, with the support and expertise of our registered nutritionists and clinicians, they were able to make this transition safely and effectively.

Check my eligibility

Do you lose more weight on Ozempic or Wegovy?

Switching from Ozempic to Wegovy will be a positive for many people looking to lose weight in the long term.

Data from randomised controlled trials shows that Wegovy generally leads to more weight loss due to the higher doses of semaglutide available.

One study found that Wegovy 2.4 mg led to an average weight loss of ~14% of body weight after 40 weeks of treatment.

In comparison, research on Ozempic 1 mg suggests it can support an average weight loss of ~6% after 40 weeks, ~8% less than Ozempic.

So, Wegovy generally leads to more weight loss than Ozempic due to the higher doses of semaglutide available.

Switching from Ozempic to Wegovy on Second Nature

Second Nature has two medication-supported programmes: a Wegovy weight-loss programme and a Mounjaro weight-loss programme.

If you’ve made the decision to try Wegovy or Mounjaro (assuming you’re eligible), why should you choose Second Nature over other medication providers?

For peace of mind.

Second Nature has worked with the NHS for over 6 years providing weight-loss programmes across the UK.

Whilst our Wegovy and Mounjaro weight-loss programmes are private and not currently used by the NHS, we’ve built the programmes with a focus on scientific evidence, patient safety, and data security.

We hope that our 6+ years of working with the NHS and building a track record of effective weight-loss results will give you peace of mind to give us a try.

Meal Plan

Maximise your weight loss on Wegovy/Mounjaro with our free 7-day meal plan

Get expert advice from our team of registered dietitians to make losing weight feel easier while on medication. Subscribe to our newsletter to get access today.

I've read and agreed to the Terms of Service & Privacy Policy.

You might also like

Make losing weight feel Second Nature

The first step on your Second Nature journey is to take our health quiz.

Hand holding phone

Write a response

As seen on

The GuardianThe TimesChannel 4The Sunday Telegraph
Evening Standard