What determines Mounjaro’s cost in the UK?
The price you’ll pay for Mounjaro in the UK depends on three key factors:
- Provider type: Online-only pharmacies (lowest cost) vs. comprehensive programmes with registered healthcare professionals (higher initial cost)
- Dosage level: Starting doses (2.5mg) cost less than maintenance doses (15mg), though many providers now offer flat-fee structures regardless of dose
- Support included: Programmes including dietitian support, habit-change coaching, and structured guidance cost more but typically show better long-term outcomes
Your choice will depend on both your budget and whether you want support developing healthy habits alongside taking the medication.
Mounjaro cost comparison across UK providers (July 2025)
Provider |
Monthly Cost (Starting) |
Monthly Cost (Highest Dose) |
What’s Included |
Dietitian Support? |
Loyalty Pricing? |
Second Nature |
£129 first month, then £239 |
Flat £239 (reduces quarterly to £199) |
Medication + full dietitian support |
✓ (5 days/week) |
✓ (£10 off quarterly) |
Boots |
£225 |
£265 |
Medication only |
✗ |
✗ |
Superdrug |
£220 |
£257 |
Medication only |
✗ |
✗ |
Asda Online Doctor |
£175 |
£215 |
Medication only |
✗ |
✗ |
Juniper |
£199 |
£239 |
Medication + coaching |
✓ |
✗ |
Voy |
£185 |
£229 |
Medication + coaching |
✓ |
✗ |
Prices accurate as of July 2025. All providers require an online consultation before prescription.
Second Nature’s loyalty-based Mounjaro pricing
Second Nature has introduced a loyalty-based pricing model that rewards your commitment to long-term health improvements:
- First month: £129 (£110 off standard price)
- Months 2-3: £239 per month
- Months 4-6: £229 per month (£10 loyalty discount)
- Months 7-9: £219 per month (£20 loyalty discount)
- Months 10-12: £209 per month (£30 loyalty discount)
- Month 13+: £199 per month (£40 loyalty discount)
This approach recognises that sustainable weight management is a journey, not a quick fix. You can cancel anytime without additional charges.
Mounjaro vs other weight-loss medications: Cost and effectiveness comparison
When considering Mounjaro, many people want to know how it compares to other weight-loss medications in terms of both cost and effectiveness. Here’s how they stack up:
Medication |
Drug |
Monthly Cost Range (UK) |
Average Weight Loss |
Mechanism |
Mounjaro |
Tirzepatide |
£175-£299 |
~15-25% body weight |
GLP-1 and GIP agonist |
Wegovy |
Semaglutide |
£160-£250 |
~15% body weight |
GLP-1 agonist only |
Saxenda |
Liraglutide |
£150-£250 |
~5-10% body weight |
GLP-1 agonist only |
Orlistat |
Orlistat |
£20-£40 |
~3% body weight |
Fat absorption inhibitor |
According to clinical trials published in the New England Journal of Medicine, Mounjaro (tirzepatide) shows higher average weight loss than other available medications, which may justify its higher cost for some people.
NHS funding for Mounjaro
Currently, the NHS only funds Mounjaro (tirzepatide) for patients living with type 2 diabetes management, not for weight loss.
Mounjaro is available on the NHS for people living with type 2 diabetes and obesity.
However, a recent NICE announcement has confirmed that Mounjaro will only be available for 250,000 people living with obesity over the next three years; this will primarily be for people with the highest BMIs alongside other obesity-related comorbidities.
NICE will review the drug’s impact and cost-effectiveness after three years to determine the next steps and whether more will become available.
On the NHS, Mounjaro (the drug in Mounjaro is tirzepatide) is only available for people with a BMI over 35, and those defined as having the “greatest clinical lead.”
So, if you want to get Mounjaro but aren’t eligible via the NHS, you may need to purchase it privately.
What is Mounjaro?
Mounjaro is a dual-function medication for individuals living with type 2 diabetes and obesity. The drug in Mounjaro is tirzepatide.
Tirzepatide is sold under the brand name Mounjaro in the UK, or Zepbound for obesity in the U.S., and manufactured by the pharmaceutical company Eli Lilly.
Tirzepatide mimics two hormones in the body: GLP-1 and glucose-dependent insulinotropic polypeptide (GIP).
When we eat food, our gut releases a hormone that helps the body regulate hunger and blood sugar levels. This hormone is called GLP-1 (glucagon-like peptide-1).
The actions of GLP-1 are the target of Mounjaro and other medications like Wegovy, Saxenda, and Ozempic.
This class of medications are known as GLP-1 receptor activators (GLP-1s). They mimic the actions of the hormone GLP-1 to activate the GLP-1 receptors.
GLP-1s improve insulin function to lower blood sugar levels and delay gastric emptying, decreasing appetite. GLP-1s also communicate with the brain’s appetite control centre, the hypothalamus, to reduce food-seeking behaviour.
Separately to GLP-1s, the other hormone that Mounjaro mimics is called GIP.
GIP is a hormone released in response to food that helps regulate blood sugar levels and helps our fat cells ‘absorb’ more excess energy, preventing fat from being stored in the liver or pancreas.
GIP also has receptors in the brain, similar to GLP-1, and scientists believe it’s also involved in regulating appetite.
The medications that mimic GIP are known as GIP mimetics. These additional actions are the target of Mounjaro.
So, tirzepatide has a dual function that mimics two hormones in the body that support blood glucose levels and weight loss.
How do you get a Mounjaro prescription in the UK?
For Second Nature’s Mounjaro programme, you’ll qualify for Mounjaro if you have a BMI of over 27 and also meet other eligibility criteria.
However, we’re unable to share this information online, and you must complete our health quiz first for us to check your eligibility.
If you’re living with type-2 diabetes, to receive a Mounjaro (tirzepatide) prescription via the NHS in the UK, here are the eligibility criteria confirmed by NICE:
- Triple therapy with metformin and two other oral antidiabetic drugs is ineffective, not tolerated or contraindicated, and
- they have a body mass index (BMI) of 35 kg/m² or more and specific psychological or other medical problems associated with obesity,
- or they have a BMI of less than 35 kg/m², and:
- insulin therapy would have significant occupational implications, or
- weight loss would benefit other significant obesity-related complications.
Lower BMI thresholds (usually reduced by 2.5 kg/m²) apply for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean family backgrounds.
To qualify for a Mounjaro prescription on the NHS if you’re living with obesity, here are the prescription requirements outlined by NICE:
- BMI of 35kg/m² or more (obesity),
- as well as those with a BMI between 27-30kg/m² (overweight) who also have weight-related health problems such as prediabetes, high blood pressure, high cholesterol, or heart problems.
- You’ll need to meet additional eligibility criteria that we can’t outline in this article
- Mounjaro’s availability on the NHS will be reserved for those with the “greatest clinical need”
Does Mounjaro have side effects?
All medications have potential side effects, and Mounjaro is no different. The most common side effects of Mounjaro are nausea, constipation, vomiting, and other symptoms affecting the gastrointestinal (GI) tract, like diarrhoea.
You might also experience less common side effects like tiredness or headaches.
These symptoms most commonly occur around the time of the injection, during dose escalation, and are typically transient and will ease after you’ve adapted to the medication.
However, everyone responds differently to these medications; some people won’t experience any side effects, while others will have to discontinue their medication due to the discomfort the side effects cause.
Is Mounjaro a magic pill?
Weight-loss injections are most effective when combined with a healthier lifestyle. They can help kickstart weight loss while you commit to developing healthier habits.
Mounjaro and other weight loss injections, like Ozempic and Wegovy, can allow you to make lifestyle changes to support long-term weight loss.
These medications can help silence food-related thoughts and give you a boost of confidence with more immediate weight-loss results.
They can also buy you the time and headspace to understand why your body may have struggled to lose weight and build new long-term healthy habits.
The core focus of our medication programmes is to calm down the feeling of food noise, lower your cravings, and allow you to build healthier habits to keep the weight off for good.
The ultimate goal is to make losing weight feel second nature.
Frequently asked questions about Mounjaro costs
How much does Mounjaro cost per month in the UK?
Mounjaro costs between £175-£299 per month in the UK depending on the provider and what support is included.
Online-only pharmacies like Asda Online Doctor offer the lowest prices (starting at £175), while comprehensive programmes with dietitian support like Second Nature cost more (£239 with loyalty discounts over time).
Is Mounjaro available on the NHS for weight loss?
Currently, Mounjaro is only widely available on the NHS for treating type 2 diabetes, not specifically for weight loss.
According to recent NICE guidelines, Mounjaro will be available to approximately 250,000 people with obesity over the next three years, primarily those with the highest BMIs and obesity-related health conditions.
Most people seeking Mounjaro specifically for weight loss will need to access it through private providers.
Why does Mounjaro cost more with Second Nature than at pharmacies?
Second Nature’s higher initial cost includes both the Mounjaro medication and comprehensive support from registered dietitians and nutritionists.
While online pharmacies only provide the medication itself, Second Nature’s programme includes daily access to healthcare professionals, personalized guidance, and habit-change support designed to maximize your results and help maintain weight loss long-term.
The programme also offers loyalty pricing that decreases your monthly cost over time, reaching as low as £199 per month after a year.
How does Mounjaro’s cost compare to other weight loss medications?
Mounjaro is generally more expensive than other weight loss medications, with UK prices ranging from £175-£299 monthly compared to Wegovy (£160-£250), Saxenda (£150-£250), and Orlistat (£20-£40).
However, clinical trials show Mounjaro typically produces greater weight loss (15-25% of body weight) compared to alternatives, which may justify the higher cost for some people seeking more significant results.
Does Second Nature’s loyalty pricing for Mounjaro have any catches?
No, Second Nature’s loyalty pricing has no catches or hidden fees. The pricing structure simply rewards longer-term commitment to your health journey, with automatic £10 quarterly discounts that can reduce your monthly cost from the standard £239 to as low as £199 by your second year.
You can cancel anytime without penalty, though you would lose the accumulated loyalty discounts if you later rejoin.
Are there Mounjaro stock shortages in the UK?
While some UK providers have experienced intermittent Mounjaro supply issues, Second Nature maintains consistent medication availability through our established pharmaceutical partnerships.
We’ve developed robust supply chain arrangements specifically designed to ensure continuous medication access for our members, with multiple sourcing options in place to prevent disruptions.
This reliability is a key advantage of our programme, as medication consistency is crucial for achieving optimal weight loss results and minimising treatment interruptions.
Take home message
Mounjaro costs vary significantly across UK providers in July 2025, ranging from £175 for medication-only services to £239 for comprehensive programmes with registered dietitian support.
While online pharmacies offer the lowest upfront price, Second Nature’s loyalty-based pricing model provides increasing discounts over time, rewarding long-term commitment to your health journey.
Research consistently shows that combining medication with professional support leads to better sustained weight loss outcomes, though the right choice depends on your personal needs, budget, and weight loss goals.
If you’re considering Mounjaro, take time to compare not just the price but also the level of support included, as this significantly impacts both your experience and long-term success with the medication.
Second Nature's Mounjaro programme
Second Nature provides Mounjaro as part of our Mounjaro weight-loss programme
Why choose Second Nature over other medication providers, assuming you’re eligible?
Because peace of mind matters.
We’ve had the privilege of working with the NHS for over eight years, helping people across the UK take meaningful steps toward a healthier, happier life.
Our programmes are designed to meet people where they are, whether that means support with weight loss through compassionate one-to-one health coaching, or access to the latest weight-loss medications (like Mounjaro) delivered alongside expert care from a multidisciplinary team of doctors, psychologists, dietitians, and personal trainers.
At the heart of everything we do is a simple belief: real, lasting change comes from building better habits, not relying on quick fixes. We’re here to support that change every step of the way.
With over a decade of experience, thousands of lives changed, and a long-standing record of delivering programmes used by the NHS, we believe we're the UK’s most trusted weight-loss programme.
We hope to offer you something invaluable: peace of mind, and the support you need to take that first step.