At-a-glance comparison
| Feature |
Second Nature |
Lloyds Pharmacy |
| Core approach |
Medication + comprehensive habit change programme |
Medication + weekly digital coaching + monthly pharmacist check-ins |
| Professional support |
Daily access to registered dietitians/nutritionists |
Weekly coach via Liva app + monthly pharmacist reviews |
| Support format |
Digital coaching via app with group support |
Digital coaching via Liva app with peer groups + pharmacist check-ins |
| Wegovy pricing (2025) |
£149-£249 a month for Wegovy (£50 off first month) |
£150-£299 monthly depending on dose |
| UK locations |
Digital-first nationwide programme |
1,500+ physical branches plus online service |
| NHS partnership |
NHS-commissioned since 2017, supports 250,000+ patients |
No NHS partnerships for weight management |
| Customer satisfaction |
4.6/5 on Trustpilot (7,600+ reviews) |
4.4/5 on Trustpilot (16,000+ reviews) |
| Medication options |
Wegovy and Mounjaro |
Wegovy and Mounjaro |
Service structure comparison
Lloyds Pharmacy has enhanced its weight loss services in 2025, evolving beyond basic prescription delivery to include structured clinical support and behaviour change coaching.
Their weight management service now includes:
- Initial BMI assessment and eligibility check
- Monthly clinical review appointments with pharmacists
- Weekly professional coaching via the Liva Healthcare platform
- Digital lifestyle tracking tools
- Peer group support via the Liva app
- Access to 1,500+ UK branches for face-to-face support
This represents an improvement over medication-only services, bringing Lloyds Pharmacy closer to a full programme rather than just medication.
Second Nature provides:
- Daily access to registered dietitians/nutritionists (five days a week)
- Psychology-based habit formation programme
- Small group support with peers on similar journeys
- Structured educational content and practical tools
- Custom-built app with tracking features
- Regular progress reviews and personalized guidance
The fundamental difference is in frequency and depth of support. Lloyds Pharmacy’s weekly coaching supplements monthly clinical oversight, while Second Nature’s daily expert access addresses the psychological and behavioural aspects of weight management with a higher level of support.
Support and professional guidance
When taking Wegovy, the type and frequency of support can significantly impact both your experience and long-term results.
Lloyds Pharmacy’s enhanced support
Lloyds Pharmacy provides a two-tier support system:
- Monthly pharmacist-led clinical oversight that focuses on:
- Medication safety monitoring
- Side effect management
- Dose adjustments when needed
- Prescription renewals
- Weekly digital coaching via the Liva Healthcare platform:
- Lifestyle guidance and goal-setting
- Basic behavioural support
- Digital tracking tools
- Peer community access
This approach ensures you receive professional medical supervision throughout your treatment with additional weekly coaching to help address lifestyle changes.
Second Nature’s comprehensive approach
Second Nature combines clinical oversight with daily behavioural support that includes:
- Guidance from registered dietitians/nutritionists available five days a week
- Personalised advice for managing side effects through food choices
- Strategies for navigating social situations while on medication
- Psychological techniques for changing long-term eating patterns
- Community support from others experiencing similar challenges
- Practical tools for building sustainable habits
Research published in the Practical Diabetes showed that engagement level significantly impacts weight loss outcomes.
Their study found that participants with high engagement levels with all aspects of the application achieved 9.5kg weight loss after 12 months compared to low engagers who achieved 6.7kg, a 42% improvement.
As shown in the research, support interactions had the strongest correlation with weight loss success. Participants with high support engagement with their health coach achieved 9.3kg weight loss compared to just 5.8kg for those with low support engagement, a 60% difference.
Our recent study published in JMIR Formative Research specifically examined outcomes from our Wegovy programme.
The results showed that our members lost an average of 19.1% after on year, which is around 3-6% more than reported in the clinical trials on Wegovy where additional support was limited.
2025 price analysis
Recent industry-wide price changes have affected all UK Wegovy and Mounjaro providers, making it essential to understand current costs.
Wegovy pricing comparison
| Dose |
Lloyds Pharmacy |
Second Nature |
| Starting dose |
£150/month |
£149/month (£99 first month) |
| 1.7mg |
~£225/month |
£199/month |
| 2.4mg |
~£299/month |
£249/month |
| First 3 months |
~£675 |
£447 (with first month discount) |
| 6-month total |
~£1,500 |
£1,244 (with first month discount) |
Note: Lloyds Pharmacy prices are approximate based on current published ranges. Exact pricing may vary.
While both providers offer the medication at similar price points, Second Nature’s first month discount makes their programme more affordable in the initial stages.
The value equation
When considering value rather than just price, important factors include:
- Support frequency (daily vs weekly/monthly)
- Professional expertise (dietitians/nutritionists vs digital coaches/pharmacists)
- Long-term habit development
- Post-medication transition planning
Weight regain research
The scientific evidence on weight maintenance after stopping GLP-1 medications highlights the importance of developing sustainable habits during treatment.
Post-medication weight trends
A landmark study published in the Diabetes, Obesity, and Metabolism tracked participants after they stopped semaglutide (Wegovy):
- Average weight loss after 68 weeks on medication: 17.3%
- Average weight after 52 weeks post-medication: 5.6% below baseline
- Weight regained: 11.6% (67% of lost weight)
This research demonstrates that without addressing underlying habits, significant weight regain is common after stopping medication.
Customer experience
Both providers receive positive reviews overall, but customer feedback highlights different strengths and limitations.
Lloyds Pharmacy feedback
Recent Trustpilot reviews for Lloyds Pharmacy (4.4/5 stars across 16,000+ reviews) highlight:
Strengths:
- Fast medication delivery
- Professional in-branch staff
- Convenience of physical locations
- Clear consultation and follow-up
- Flexible digital and in-person options
Limitations:
- Occasional delivery delays following logistics changes
- Communication delays during busy periods
- Variable experience depending on local branch
- Limited out-of-hours support
Second Nature feedback
Second Nature maintains a 4.6/5 Trustpilot rating across 7,600+ reviews, with consistent positive feedback about:
Strengths:
- Responsive support from health coaches
- Depth of nutritional guidance
- Supportive peer community
- Practical strategies for habit change
- Comprehensive educational content
Limitations:
- Digital-only approach (no physical locations)
- Learning curve for app features
- Group support format not ideal for everyone
This comprehensive approach is reflected in member testimonials. As one Second Nature participant shared:
“Having carried out lots of research, I opted to do my medicated weight loss program with Second Nature. Each day there is information to listen to or read (whichever is your preference) to educate you on food, eating right, being healthy … to retrain and learn how to make the right choices once a healthy weight is reached.
The support of my coach Monet has been so useful, in motivating me to eat enough protein, to exercise, to query my past and present food choices.
These support mechanisms, the medication itself, and the support of my group (sharing our experiences on the journey) are empowering me to know that this time my yo-yo dieting past is behind me and a healthier me is already emerging. Thank you Second Nature!”
This firsthand experience highlights how the combination of daily education, coach support, and group community creates a framework for sustainable change beyond medication alone.
NHS partnership
Second Nature’s NHS partnerships and six-year history of delivering NHS-commissioned services demonstrate a commitment to high clinical standards and evidence-based practice.
Since 2017, Second Nature has:
- Supported over 250,000 NHS patients
- Been commissioned by more than two-thirds of UK NHS Health and Care boards
- Published peer-reviewed research on programme outcomes
- Expanded our services to tier 3 weight management across the UK that includes a Mounjaro prescription
- Received NICE approval for digital weight management
The National Institute for Health and Care Excellence (NICE) announcement that Wegovy would be available via digital weight management services provided by Second Nature and three other companies supporting the NHS recognises the high level of patient care and professional standards.
While Lloyds Pharmacy is a respected UK pharmacy chain with over 1,500 branches, it doesn’t currently deliver NHS-commissioned weight management programmes, which means its weight loss services haven’t undergone the same level of NHS evaluation and approval.
Which programme should you choose?
Consider Second Nature if you:
- Value daily expert support from registered dietitians rather than weekly coaching
- Want guidance from registered dietitians/nutritionists
- Need intensive habit change support
- Are concerned about maintaining results after medication
- Have struggled with emotional or habitual eating
- Value programmes with NHS validation
- Prefer a psychology-based approach to behaviour change
Consider Lloyds Pharmacy if you:
- Prefer face-to-face interactions at physical locations
- Value the convenience of in-branch appointments
- Feel weekly coaching provides sufficient support
- Are comfortable with primarily digital coaching via the Liva app
- Want the option of both online and in-person service
- Prefer pharmacist-led clinical oversight
- Need more flexibility in appointment scheduling
Frequently asked questions
How often will I meet with a healthcare professional with each provider?
With Second Nature, you’ll have daily access to a registered dietitian or nutritionist five days a week through the app, plus regular check-ins about your medication.
With Lloyds Pharmacy, you’ll have weekly coaching via the Liva app and monthly scheduled appointments with a pharmacist, either online or in-person at one of their 1,500+ branches.
What happens if I experience side effects?
Lloyds Pharmacy provides pharmacist consultations for side effect management, with the ability to book appointments when needed.
Second Nature offers immediate support through dietitians who can provide specific food strategies to manage nausea and other common side effects, plus access to a supportive community who can share their experiences.
Will I keep the weight off after stopping medication?
Research shows 67% of weight is typically regained after stopping Wegovy without adequate habit change. Second Nature’s daily support and comprehensive behaviour change programme is specifically designed to develop the habits needed for long-term maintenance, with preliminary data showing significantly less weight regain.
Lloyds Pharmacy’s weekly coaching and monthly check-ins provide some behavioural support, but with less intensity than daily guidance.
How do I know which option is right for me?
Consider your past weight loss attempts and what support you’ve found most helpful. If you’ve struggled with emotional eating or found it difficult to maintain weight loss in the past, Second Nature’s comprehensive approach may be beneficial.
If you value in-person pharmacy access and feel weekly coaching is sufficient, Lloyds Pharmacy may be suitable for your needs.
Can I switch providers if I’m not satisfied?
Yes, you can request your prescription records from either provider and transfer to another service. However, be aware that starting fees may apply again, and there may be a new consultation process with the new provider.
Take home message
Research suggests that Second Nature’s daily access to registered dietitians delivers measurably better outcomes than less frequent support models.
Both Second Nature and Lloyds Pharmacy offer legitimate ways to access Wegovy in the UK, but with different approaches to supporting your weight loss journey.
Lloyds Pharmacy combines monthly pharmacist check-ins with weekly digital coaching via their Liva Healthcare platform, plus the convenience of 1,500+ physical locations, making it suitable for those who value face-to-face interactions and feel weekly coaching provides adequate support.
Second Nature offers daily access to registered dietitians, a psychology-based habit change programme, and peer support, providing a more intensive approach for those concerned about long-term results and post-medication maintenance.
Research indicates that support frequency significantly impacts outcomes, particularly after stopping medication, with more frequent engagement showing better long-term weight maintenance than weekly or monthly check-ins alone.
Your choice should ultimately reflect your personal needs, past experiences with weight management, and the level of support you believe will help you develop sustainable habits for lasting results.
Second Nature's Mounjaro and Wegovy programmes
Second Nature provides Mounjaro or Wegovy as part of our Mounjaro and Wegovy weight-loss programmes.
Why choose Second Nature over other medication providers, assuming you're eligible?
Because peace of mind matters.
We've had the privilege of working with the NHS for over eight years, helping people across the UK take meaningful steps toward a healthier, happier life.
Our programmes are designed to meet people where they are, whether that means support with weight loss through compassionate one-to-one health coaching, or access to the latest weight-loss medications (like Mounjaro and Wegovy) delivered alongside expert care from a multidisciplinary team of doctors, psychologists, dietitians, and personal trainers.
At the heart of everything we do is a simple belief: real, lasting change comes from building better habits, not relying on quick fixes. We're here to support that change every step of the way.
With over a decade of experience, thousands of lives changed, and a long-standing record of delivering programmes used by the NHS, we believe we're the UK's most trusted weight-loss programme.
We hope to offer you something invaluable: peace of mind, and the support you need to take that first step.
