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How quickly do you lose weight on Mounjaro?

Robbie Puddick
Written by

Robbie Puddick

Medically reviewed by

Fiona Moncrieff

4 min read
Last updated December 2024
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Jump to: How much weight can you lose on Mounjaro in a month? | How do I maximise my weight loss on Mounjaro? | Does Mounjaro have side effects?

According to randomised controlled trials, you start losing weight immediately after taking Mounjaro.

Mounjaro (tirzepatide) reduces appetite and hunger, helping you eat fewer calories; this effect is almost immediate.

However, you might notice the impact of lower hunger wearing off after 4-5 days post-injection in the first month of taking Mounjaro.

It can take around four weeks for Mounjaro to reach a level in the body we call a steady state. A steady state is when the drug’s levels in the body remain consistent rather than spiking and falling.

Interestingly, this initial weight loss is no different to other weight loss treatments or the impact of diet interventions on weight loss. The real effect of Mounjaro is seen beyond three months.

Mounjaro is a long-acting medication that’s started at a lower dose to reduce the number and severity of side effects as it’s built up to a higher maintenance dose.

Medication-assisted weight loss with a future focus

Start with Wegovy or Mounjaro, transition to habit-based health with our support

Mounjaro pen
Wegovy pen

How much weight can you lose on Mounjaro in a month?

According to data from randomised controlled trials, Mounjaro supports weight loss of around 4% of body weight after one month. After two months, it’s around 6% of body weight.

A graphic showing how much weight you can lose in a month on Mounjaro. It also shows how much weight you can lose after two months on Mounjaro.

However, as this is an average rate of weight loss, it’s unclear how much weight loss an individual will lose in a month on Mounjaro. Some people may lose weight quickly, while others may take longer.

Tirzepatide (the active ingredient in Mounjaro) reduces appetite and hunger, helping you eat fewer calories; this effect is almost immediate.

However, you might notice the effect of lower hunger wearing off after 4-5 days post-injection in the first month of taking Mounjaro.

It can take 4-5 weeks for Mounjaro to reach a level in the body we call a steady state. A steady state is when the drug’s levels in the body remain consistent rather than spiking and falling.

Interestingly, this initial weight loss is no different to other weight loss treatments or the impact of diet interventions on weight loss. The real effect of tirzepatide is seen beyond three months.

Tirzepatide is a long-acting medication that’s started at a lower dose to reduce the number and severity of side effects as it builds up to a higher maintenance dose.

How do I maximise my weight loss on Mounjaro?

To maximise weight loss on Mounjaro, it’s recommended to introduce healthy habits such as eating a healthy diet based on whole foods, being more physically active, and sleeping well.
The drug in Mounjaro is called tirzepatide. Tirzepatide mimics two hormones in the body that help us feel less hungry, so we eat fewer calories and lose weight.
However, without the introduction of healthy habits, it’s possible you won’t maximise your potential weight loss on the medication and may experience more side effects.

Does Mounjaro have side effects?

The most common side effects of Mounjaro are nausea, constipation, vomiting, and other symptoms affecting the gastrointestinal (GI) tract, like diarrhoea.

You might also experience less common side effects like tiredness or headaches.

These symptoms most commonly occur around the time of the injection, during dose escalation, and are typically transient and will ease after you’ve adapted to the medication.

However, everyone responds differently to these medications; some people won’t experience any side effects, while others will have to discontinue their medication due to the discomfort the side effects cause.

Mounjaro isn’t a magic pill

Weight-loss injections are most effective when combined with a healthier lifestyle. They can help kickstart weight loss while you commit to developing healthier habits.

Mounjaro and other weight loss injections, like Ozempic and Wegovy, can allow you to make lifestyle changes to support long-term weight loss.

These medications can help silence food-related thoughts and give you a boost of confidence with more immediate weight-loss results.

They can also buy you the time and headspace to understand why your body may have struggled to lose weight and build new long-term healthy habits.

The core focus of our medication programmes is to calm down the feeling of food noise, lower your cravings, and allow you to build healthier habits to keep the weight off for good.

The ultimate goal is to make losing weight feel second nature.

Second Nature’s medication-supported programmes

Second Nature has two medication-supported programmes: a Wegovy weight-loss programme and a Mounjaro weight-loss programme.

If you’ve decided to try Wegovy or Mounjaro (assuming you’re eligible), why should you choose Second Nature over other medication providers?

For peace of mind.

Second Nature has worked with the NHS for over 6 years providing weight-loss programmes across the UK.

Whilst our Wegovy and Mounjaro weight-loss programmes are private and not currently used by the NHS, we’ve built the programmes with a focus on scientific evidence, patient safety, and data security.

We hope that our 6+ years of working with the NHS and building a track record of effective weight-loss results will give you peace of mind to give us a try.

Medication-assisted weight loss with a future focus

Start with Wegovy or Mounjaro, transition to habit-based health with our support

Mounjaro pen
Wegovy pen

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Write a response

Carmen

5 September, 2024

Please send me info about pricing


Lisa Engels

18 February, 2024

I’m been using Mounjaro for 9 months
I lost 40 pounds on my own over 5 years before starting the injections
In April of 2023 I weighed 170 pounds and my a1c was around 8. I was using Lantas, Humalog, Trulicity and Jardiance
As of February 2024 I’m down to 118 pounds (high school weight), a1c is 5.1 (not even pre-diabetes)
I was up to 12.5 of Mounjaro and now on 10 maintenance dose.
I had nausea the first 2 months and surprised at how little I eat and still have energy
If you love to eat this is not a regimen for you
It’s more of a reminder to self to eat
Good luck in your journey


Sc

17 February, 2024

I started Mounjour 5 days ago. I lost 9lbs already! I immediately felt my appetite decrease, however, I also had some side affects. I felt the sensitivity when I injected, I also felt headaches and the tireness. No nausea or diarrhea. I have been drinking more water and staying hydrated. I am avoiding the sugary drinks and eating less carbs as well. I would highly recommend reading about Mounjour for the side affects and monitor how you are feeling. I am approaching my weight loss journey as a life style change and not solely relying on Mounjour to do the work alone. Look forward to my first month progress!


Barbara

15 December, 2023

I just started the mounjaro. My appetite was affected immediately. I have to force myself to eat in order to take other medications. I’m not sure if I should continue this or not. I’m going to try it for 30 days & see how it works.


Linda

8 September, 2024

I’m a little behind on taking Monjuro since the last thing I see posted was February. I started this medication injectable beginning of August. I am already down 16 pounds. I’m starting now on my 5 mg. I’m finding that I don’t want to eat at all. I’m actually having trouble eating drinking a lot of water lemon water to be exact. I have been working out. I started right off the bat cutting our carbs and eating light and exercising. I don’t know if that helps but I didn’t wanna lose weight and have any kind of saggy skin and I figured it would help all around to keep me going after I stop this medication. I don’t have really any symptoms I have some nausea every once in a while bathroom OK I’m going to the bathroom OK. I’m just concerned about this lack of appetite. I feel like I can go all day without eating and not bothering me. Has anybody else experience this?


Sandy

1 October, 2024

Hi Linda, this is my 2nd week, and yes I know I just started but I don’t feel hungry at all, I’m happy about that. 😀

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