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Boots vs Second Nature

Robbie Puddick
Written by

Robbie Puddick

Medically reviewed by

Fiona Moncrieff

5 min read
Last updated September 2023

Jump to: Should I buy Wegovy online? | Weight regain with Wegovy | Second Nature’s NHS-trusted | Cost and Trustpilot reviews | Take home message

Whether you choose Boots or Second Nature to help you lose weight with Wegovy will depend on the level of support you feel you need to keep the weight off for good. 

Boots offers a free 10-week online programme with written and video content to support patients in losing weight whilst on Wegovy.

Whereas Second Nature’s medication-supported programme is similarly priced, a bit more comprehensive, and comes with the following benefits you won’t get with a Boots Wegovy prescription:

  • Peace of mind that we’ve been trusted by the NHS since 2017 to provide weight-loss services
  • Access to a registered nutritionist or dietitian five days a week
  • Science-backed articles to help you keep the weight off for good

If you want to see your eligibility for our programme when it launches, click here to join our waiting list.

Should I buy Wegovy online?

Wegovy is designed as an additional tool for weight management and shouldn’t be considered a lifelong medication.

Instead, it should be used to help you kickstart your weight loss and healthy journey while you commit to living a healthier lifestyle.

Ideally, we’d be able to lose weight without medication and lifestyle changes would be enough to support weight loss in the long term.

We’d generally recommend trying Second Nature’s weight-loss programme before considering a weight-loss jab.

Changing your habits is the most sustainable way to achieve long-term weight loss, and it’s also less expensive (£40 a month vs. ~£299 a month).

At Second Nature, we’ve been trusted by the NHS since 2017 to support people with type 2 diabetes and obesity to lose weight, manage their blood sugar levels, and lead healthier lifestyles for the long term.

In 2022, the NHS published data in the BMJ that compared the weight loss outcomes of five providers in the National Diabetes Prevention Programme.

Second Nature was more than twice as effective at supporting weight loss than the other four providers.

However, if you’ve decided to try Wegovy (when it’s available) but need support in making positive changes to your lifestyle, Second Nature could be an option for you. But it’s worth noting that we have strict eligibility criteria.

We’ll launch our medication-supported programme soon when semaglutide becomes available; click here to join our waiting list.

Otherwise, keep reading as we look at three critical differences between Second Nature’s medication-supported programme and Boots.

1) Weight regain with Wegovy is likely without the proper support

Like traditional diets, where participants typically regain weight once the diet program ends, weight regain is significant following the cessation of semaglutide.

The greater the initial weight loss, the more significant the weight regained.

However, those who lose more weight initially maintain more significant weight loss compared to baseline than those who lose less before the medication is withdrawn.

In this post-analysis of 327 participants, the average weight loss after 68 weeks was 17.3% with semaglutide and 2% with placebo.

After 52 weeks of follow-up, after the medication was withdrawn, the average weight loss was 5.6% with semaglutide and 0.1% with placebo.

A weight regain of 11.6% in the semaglutide group and 1.9% in the placebo.

Weight regain isn’t inevitable. Long-term sustainable weight loss can be achieved, but you need the proper support.

Unfortunately, if you feel you need more support to help you maintain weight loss in the long run, you might not get this on the Boots programme as you don’t have access to a peer support group or a registered nutritionist. 

It’s possible that when you come off of the medication, you’ll regain much of the weight lost without making significant changes to your habits and lifestyle. 

But higher levels of support are something that Second Nature can offer, and the fact we’ve been trusted by the NHS since 2017 to provide weight-loss services showcases the long-term impact Second Nature has had on our members. 

2) Second Nature’s NHS-trusted and NICE-approved

Second Nature has been trusted by the NHS since 2017. We’ve delivered programmes for the NHS in type 2 diabetes management, diabetes prevention, and weight management.

The National Institute of Health and Care Excellence (NICE) recently announced that Wegovy would be available via digital weight management services provided by Second Nature and three other companies supporting the NHS.

This approval recognises the high level of patient care and support that Second Nature has provided our members.

This approval recognises the high level of patient care and support that Second Nature has provided our members.

Additionally, we have over 6 years of clinical data showcasing our programme’s positive impact on weight loss and type 2 diabetes management. 

Boots’ new programme is evidence-based and developed by registered healthcare professionals with a similar style and tone to Second Nature’s programme. 

However, it hasn’t been clinically tested or used in the NHS, and its impact on long-term weight loss is unclear.

3) Wegovy cost and Trustpilot reviews

  • The total monthly cost of the Second Nature programme, including semaglutide medication, is £229, rising to £299
  • The total monthly cost of Wegovy from Boots is £199, rising to £299
  • This means all of the additional benefits you receive with Second Nature’s programme only cost an extra £30 a month at the start and rise to the same price as a Boots prescription
  • Second Nature’s current Trustpilot score based on 6,270 reviews is 4.8, and are rated as ‘Excellent’
  • Boots has no verified Trustpilot account

Take home message

Weight-loss injections like Wegovy (semaglutide) can be extremely effective.

With a Boots prescription, you’ll have the reassurance that you’re accessing medication from a reputable company in the UK that follows the highest clinical standards. 

Their free 10-week online programme is also evidence-based and well-presented to support weight loss. 

So, we’d recommend choosing Boots over other online pharmacies selling Wegovy, like Asda Online Doctor, Zava, HealthExpress, Mayfair Weight Loss Clinic, and Simply Meds.

However, many people may need more support from a registered dietitian and nutritionist to keep the weight off for good. 

Our internal research shows that individuals on semaglutide typically have been on the yo-yo dieting cycle for a very long time and almost consider this medication as their ‘last hope’. 

If you’ve tried to lose weight on your own in the past and it hasn’t worked, then Second Nature’s programme might be for you. 

To see if you’re eligible, you can join our waiting list here.

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