Jump to: Quick comparison | Clinical evidence | Support and coaching | Pricing | Who should choose each | FAQs | Take home message
When choosing between Voy and Second Nature for medication-supported weight loss, the most important difference comes down to clinical specialisation and the depth of evidence behind each programme.
Second Nature has focused exclusively on weight management since 2017, with NHS partnerships across 43 ICBs and Health Boards, and peer-reviewed research published in the British Medical Journal and JMIR Formative Research.
Voy launched in 2024 as a sub-brand of Manual, a men’s health company. They’ve grown quickly to over 100,000 members and have partnered with Imperial College London on outcomes research. While both services prescribe weight-loss injections, they differ in the type and level of support you receive alongside medication.
This guide was written by Second Nature, so it naturally reflects our perspective, but we’ve aimed to present Voy’s strengths and limitations as fairly as possible.
Important safety information: Weight-loss medications like Mounjaro and Wegovy are prescription-only medicines. This article is for informational purposes only. Always consult with your healthcare provider before starting any new medication or weight-loss programme.
Voy vs Second Nature: quick comparison
| Feature |
Second Nature |
Voy |
| Company focus |
✓ Weight management specialist since 2017 |
✗ Sub-brand of Manual (men’s health company, est. 2018) |
| NHS partnership |
✓ Commissioned across 43 ICBs and Health Boards |
✗ No NHS affiliations |
| Clinical evidence |
✓ Peer-reviewed research in JMIR1 |
? Internal analysis with Imperial College London (not yet peer-reviewed) |
| Professional support |
✓ Registered dietitians and nutritionists (HCPC/AfN) |
? Health coaches and clinicians (coaching qualifications not detailed publicly) |
| Trustpilot reviews |
✓ 4.5/5 from 7,800+ reviews |
✓ 4.7/5 from 17,000+ reviews |
| Behaviour change model |
✓ COM-B framework with 4-phase structured programme |
✗ No named behaviour change methodology |
| Medication options |
Mounjaro, Wegovy, Orlistat |
Mounjaro, Wegovy, Saxenda, Orlistat |
| Programme without medication |
✓ Available from £33/month |
✗ Not available |
| Peer support groups |
✓ Small group communities |
✗ Individual support only |
| Weight loss guarantee |
✗ Not offered |
✓ 10% body weight in 6 months or refund (T&Cs apply) |
Clinical evidence and NHS partnership
Second Nature: published outcomes since 2017
Second Nature has focused exclusively on weight management and behaviour change for over eight years. The NHS has commissioned our programmes since 2017, with 43 ICBs and Health Boards across the UK using our services to support over 250,000 patients.
Our published research in JMIR Formative Research shows specific outcomes for our medication-supported programme1:
- 19.1% average weight loss at 12 months
- 77.7% achieved at least 10% weight loss
- 69% reported no side effects by month 12
Separately, NHS England’s evaluation of the Digital Weight Management Programme found that Second Nature achieved substantially higher weight loss compared to other providers at 12 months2. This is independent validation from the NHS itself, not our own marketing.
Voy: growing scale with emerging research
Voy launched in 2024 as Manual’s expansion into weight loss. Manual has operated since 2018, initially focusing on men’s health treatments, including hair loss and erectile dysfunction.
Voy has grown quickly and now reports over 100,000 members. They cite an average body weight loss of 21.55% over 10 months, based on an internal analysis of nearly 58,000 participants conducted in partnership with Imperial College London.
This is a large dataset and a notable step towards clinical validation. However, this research has not yet been published in a peer-reviewed journal, which means it hasn’t undergone independent scrutiny.
There’s an important difference between internal analysis, even with a reputable academic partner, and independently reviewed and published research.
Support and coaching
Second Nature: registered dietitians and nutritionists
Second Nature provides UK-registered dietitians and nutritionists, available five days a week through both group and private messaging. These professionals are:
- Registered with the Health and Care Professions Council (HCPC) or the Association for Nutrition (AfN)
- Trained specifically in GLP-1 medication support
- Supervised by senior dietitians
- Supported by in-house psychologists on behaviour change coaching
You’re also placed in a small peer group with others on similar programmes. Research consistently shows that peer support improves weight-loss maintenance3, and this community element is built into every Second Nature membership.
Our programme follows the COM-B model (Capability, Opportunity, Motivation, Behaviour)4 and runs across four phases: Core, Grow, Maintain, and Sustain.
This structured approach is designed to help you build habits that last beyond medication, which matters because research shows around two-thirds of people regain weight within a year of stopping GLP-1 medication without behaviour change support5.
Second Nature’s app includes:
- 300+ recipes designed for weight-loss medications
- Food and mood journals identifying patterns
- Daily educational content (audio or written)
- Habit tracking with behavioural insights
- Medication management with side-effect support
Voy: health coaches, clinicians, and app-based tools
Voy provides a personal health coach alongside their clinical team, led by Chief Medical Officer Dr Earim Chaudry. Members have access to:
- A dedicated health coach for one-to-one support
- Clinician-led prescribing and treatment monitoring
- An AI-powered assistant (Joy) for day-to-day questions
- An app with AI-powered meal tracking, progress logging, and educational content
- Blood testing is available as an add-on through their Do Health platform
Voy describes their support team as “health coaches” and “clinicians”, but doesn’t publicly detail the specific qualifications or regulatory registrations of their coaching staff. This makes it difficult to directly compare the level of nutritional expertise with that of Second Nature’s registered dietitians.
Voy does not currently offer peer support groups. Their model focuses on individual coaching and app-based engagement, which some people may prefer if they want privacy rather than a group setting.
Who should choose each programme?
Choose Second Nature if you:
- Want a programme backed by published, peer-reviewed clinical research
- Value NHS-validated approaches and institutional trust
- Prefer support from registered dietitians and nutritionists
- Benefit from peer support and small group communities
- Want a structured behaviour change plan for life after medication
- Want the option of a non-medication programme
Choose Voy if you:
- Want a large, established provider with 100,000+ members and strong Trustpilot reviews
- Prefer one-to-one coaching over group-based support
- Want a weight loss guarantee with a refund option
- Value a wider range of medication options (Mounjaro, Wegovy, Saxenda, Orlistat)
- Prefer app-first engagement with AI-powered meal tracking
- Want access to blood testing through their Do Health platform
Frequently asked questions
Is Voy or Second Nature better for Mounjaro?
Second Nature provides more specialised support for Mounjaro users through registered dietitians trained in GLP-1 medications. Our published research shows 77.7% of participants achieved at least 10% weight loss at 12 months1.
Voy provides Mounjaro alongside health coaching and clinician support. They report strong outcomes from an internal analysis with Imperial College London, though this data has not yet been peer-reviewed. Both services prescribe the same medication; the difference is in the support that comes alongside it.
Does Voy have NHS approval?
No. Voy has no NHS partnerships or commissioning. Second Nature has been NHS-commissioned since 2017, with 43 ICBs and Health Boards across the UK using our services.
This NHS relationship reflects confidence in our clinical approach, governance standards, and data security. It’s worth noting that NHS commissioning is not a requirement to prescribe weight-loss medications safely; it’s an additional layer of institutional validation.
Is Manual the same company as Voy?
Yes. Voy is a sub-brand of Manual, which launched in 2018, focusing on men’s health issues, including hair loss and erectile dysfunction. Manual created Voy in 2024 to enter the weight-loss market.
Voy has since grown to over 100,000 members, operates with its own clinical team, and has invested in outcomes research through a partnership with Imperial College London.
What qualifications do Voy coaches have?
Voy describes their team as “health coaches” and “clinicians” but doesn’t publicly detail the specific qualifications or regulatory registrations of their coaching staff. Their clinical team is led by Dr Earim Chaudry, who has experience in digital health.
Second Nature employs UK-registered dietitians and nutritionists who are registered with the HCPC or AfN, with specialised training in GLP-1 medication support and supervision from senior dietitians.
Can I switch from Voy to Second Nature?
Yes. We’ll review your medical history and current medication to ensure a safe transition. A 7-day gap between your last Voy prescription and your first Second Nature prescription is usually recommended.
Many members join Second Nature after starting with other providers, seeking more structured behaviour change support alongside their medication.
Which has better customer reviews?
Both services have strong Trustpilot ratings. Voy has a 4.7/5 rating from over 17,000 reviews, reflecting its larger membership base and rapid growth. Second Nature has a 4.5/5 rating based on over 7,800 reviews, spanning eight years of operation.
The volume of positive reviews on both sides suggests genuine member satisfaction with each service. It’s worth reading recent reviews on both platforms to get a feel for the specific experiences that matter most to you.
Do both offer the same medications?
Voy offers a wider range: Mounjaro, Wegovy, Saxenda, and Orlistat. Second Nature currently offers Mounjaro and Wegovy.
Second Nature also provides a comprehensive non-medication programme from £33/month for those who prefer a lifestyle-only approach, or who want to transition off medication with structured support.
Does Voy offer a weight-loss guarantee?
Yes. Voy guarantees that you’ll lose at least 10% of your body weight in 6 months, or they’ll refund you (subject to their terms and conditions).
Second Nature does not offer a money-back guarantee. Our confidence comes from NHS-validated outcomes, peer-reviewed clinical research, and eight years of published results demonstrating the effectiveness of our approach.
Take home message
Second Nature and Voy both prescribe effective weight-loss medications at broadly comparable prices. The key difference is in what comes alongside the medication.
Second Nature brings eight years of specialist weight management experience, NHS commissioning across 43 health boards, published peer-reviewed research, and support from registered dietitians. Our structured behaviour change programme is specifically designed to help you maintain results after medication.
Voy has quickly built a large membership base, offers a wider range of medications, and provides a weight-loss guarantee. Their partnership with Imperial College London on outcomes research is a positive step towards clinical validation, though this data has not yet been peer-reviewed.
The choice comes down to what matters most to you: the depth of clinical evidence and professional qualifications behind the support, or the scale of membership, the range of medications, and the financial guarantee.
Second Nature's Mounjaro and Wegovy programmes
Second Nature provides Mounjaro or Wegovy as part of our Mounjaro and Wegovy weight-loss programmes.
Why choose Second Nature over other medication providers, assuming you're eligible?
Because peace of mind matters.
We've had the privilege of working with the NHS for over eight years, helping people across the UK take meaningful steps toward a healthier, happier life.
Our programmes are designed to meet people where they are, whether that means support with weight loss through compassionate one-to-one health coaching, or access to the latest weight-loss medications (like Mounjaro and Wegovy) delivered alongside expert care from a multidisciplinary team of doctors, psychologists, dietitians, and personal trainers.
At the heart of everything we do is a simple belief: real, lasting change comes from building better habits, not relying on quick fixes. We're here to support that change every step of the way.
With over a decade of experience, thousands of lives changed, and a long-standing record of delivering programmes used by the NHS, we believe we're the UK's most trusted weight-loss programme.
We hope to offer you something invaluable: peace of mind, and the support you need to take that first step.
References
- Richards, R., et al. (2025). A Remotely Delivered, Semaglutide-Supported Weight Management Program: 12-Month Outcomes. JMIR Formative Research, 9(1), e72577.
- Ross, J.A.D., et al. (2022). Uptake and impact of the English National Health Service digital diabetes prevention programme. BMJ Open Diabetes Research & Care, 10(3), e002736.
- Lemstra, M., et al. (2016). Weight loss intervention adherence and factors promoting adherence: a meta-analysis. Patient Preference and Adherence, 10, 1547-1559.
- Michie, S., van Stralen, M.M. & West, R. (2011). The behaviour change wheel: A new method for characterising and designing behaviour change interventions. Implementation Science, 6, 42.
- Wilding, J.P.H., et al. (2022). Weight regain and cardiometabolic effects after withdrawal of semaglutide. Diabetes, Obesity and Metabolism, 24(8), 1553-1564.
