Jump to: Quick comparison | How each service works | Clinical evidence | Support and coaching | Medication options | Pricing | Who should choose each | Frequently asked questions | Take home message
heySlim and Second Nature both offer Mounjaro and Wegovy prescriptions in the UK, but they’re different types of service.
heySlim is a doctor-led online prescription platform; Second Nature is a structured weight management programme with medication included.
heySlim positions itself as a clinician-led service that connects you with UK-registered prescribers for personalised treatment plans. Their model provides access to GLP-1 medication with medical oversight, starting at £89 per month.1
Second Nature pairs medication with a structured behaviour change programme delivered by registered dietitians and nutritionists. Published research shows 19.1% average weight loss at 12 months with semaglutide and dietitian-led coaching.2
heySlim is a relatively new entrant to the UK market. Their Trustpilot profile currently shows a 3.9/5 rating from 82 reviews, with a notable proportion of 1-star reviews alongside positive ones.
Second Nature has a 4.5/5 rating from over 7,800 reviews. This difference in both volume and rating distribution is worth considering when choosing a provider.
This guide was written by Second Nature, so it naturally reflects our perspective, but we’ve aimed to present heySlim’s strengths and limitations as fairly as possible.
Important safety information: Mounjaro (tirzepatide) and Wegovy (semaglutide) are prescription-only medications for managing obesity and overweight. This article is for informational purposes only. Always consult with your healthcare provider before starting, stopping, or switching any weight-loss medication.
heySlim vs Second Nature: quick comparison
| Feature |
Second Nature |
heySlim |
| Service type |
Structured weight management programme with medication |
Doctor-led online prescription service |
| NHS partnership |
✓ Commissioned across 43 ICBs and Health Boards since 2017 |
✗ Private service only |
| Published clinical evidence |
✓ Peer-reviewed research in JMIR and BMJ2,3 |
✗ No published programme-specific outcomes |
| Primary support model |
Registered dietitians and nutritionists (HCPC/AfN), 5 days/week via in-app messaging |
UK-registered prescribers via online consultation; doctor access for questions on side effects, nutrition, and exercise |
| Behaviour change programme |
✓ COM-B model, 4-phase structured programme with daily content |
✗ No structured behaviour change programme (blog articles and resources available) |
| Peer support |
✓ Small in-app peer support groups |
✗ Not mentioned |
| Consultation format |
Online assessment + ongoing in-app coaching |
Online health assessment + clinician consultation (video available) |
| Medication options |
Mounjaro, Wegovy (including 7.2 mg) |
Mounjaro, Wegovy (including 7.2 mg) |
| Starting price |
From £149/month (Wegovy, all-inclusive) |
From £89/month1 |
| Trustpilot rating |
4.5/5 from 7,800+ reviews |
3.9/5 from 82 reviews4 |
How each service works
heySlim: doctor-led prescription service
heySlim is a UK-based online platform that connects you with UK-registered prescribers for weight-loss medication.
The process starts with an online health assessment covering your medical history, lifestyle, and weight-loss goals. If you’re potentially eligible, you proceed to a consultation with an independent UK-registered clinician.1
If the clinician determines treatment is appropriate, they issue a prescription and medication is delivered within approximately two business days in discreet packaging.
heySlim describes itself as “doctor-led,” which it says distinguishes it from services that use pharmacist prescribers.
They state that their doctors can handle more complex cases, including patients who may have been declined by other providers.1
Alongside the prescription, heySlim provides ongoing care resources and direct access to a weight-loss doctor for questions about side effects, nutrition, and exercise. They also publish blog content on topics such as diet, switching medications, and NHS eligibility.
Second Nature: programme provider with medication
Second Nature pairs medication with a structured behaviour change programme. You’re assigned a registered dietitian or nutritionist available five days a week through in-app messaging and placed in a small peer support group.
The programme runs across four phases using the COM-B behaviour change model, covering nutrition (using a balanced plate model rather than calorie counting), physical activity, sleep, and the psychological aspects of eating behaviour. Daily educational content is delivered through the app.2
Everything is bundled into a single monthly fee: medication, delivery, coaching, app access, and peer support.
Clinical evidence
Second Nature
Second Nature has published programme-specific outcomes in peer-reviewed journals. Our 2025 study in JMIR Formative Research found2:
- 19.1% average weight loss at 12 months for active subscribers
- 77.7% achieved at least 10% weight loss
- 61.5% achieved at least 15% weight loss
- 69% reported no side effects by month 12
These are completer results, not intent-to-treat. An NHS evaluation in the BMJ also found Second Nature achieved substantially higher weight loss than four other providers in the National Diabetes Prevention Programme.3
heySlim
heySlim has not published programme-specific weight-loss outcomes in a peer-reviewed journal.
Their website references the clinical trial data for the medications they prescribe (such as up to 22.5% weight loss with Mounjaro at the highest dose over 72 weeks) rather than outcomes from their own service.1
As a newer service, this is not unusual. It does mean there’s no independently published data on how heySlim’s specific model (prescription plus doctor access and resources) compares to medication alone.
Support and coaching
This is the most significant difference between the two services.
Second Nature
Day-to-day support is provided by HCPC- or AfN-registered dietitians and nutritionists, available five days a week via in-app messaging. Health coaches receive specific training in GLP-1 side effect management. You’re placed in a small peer support group within the app.2
The programme delivers daily educational content covering nutrition, medication management, physical activity, sleep, and the psychological aspects of eating, including resources for emotional eating and stress.
heySlim
heySlim provides access to your prescribing doctor for questions about side effects, nutrition, and exercise. Their website states they offer “ongoing care resources” alongside prescriptions.1
They also publish blog content covering practical topics like what to eat on Mounjaro, how to switch between medications, and NHS eligibility. This content is freely available on their website rather than delivered through a structured programme or app.
heySlim does not offer a structured behaviour change programme, 1-to-1 dietitian coaching, or peer support groups.
Their model is closer to ZAVA’s (prescription service with medical oversight) than to programme providers like Second Nature, Voy, or Juniper.
Medication options
Both providers prescribe Mounjaro and Wegovy. heySlim’s website provides detailed information about both medications, including dose escalation schedules, side effects, and switching protocols.1
heySlim offers guidance on switching between Mounjaro and Wegovy, with a 7-day washout protocol under clinician supervision. This has become more common since Mounjaro’s September 2025 price increase.
Both providers offer Wegovy 7.2 mg, approved by the MHRA in January 2026.5
Pricing
Pricing changes, so check each provider’s website for the most current figures.
heySlim
heySlim advertises pricing “from £89 per month,” though the actual cost varies by medication and dose. The price includes the online consultation, prescriber support, and ongoing care resources. Payment is taken before the consultation, but heySlim offers a full refund if you’re found ineligible or decide not to proceed.1
Second Nature
Second Nature charges an all-inclusive monthly fee covering medication, delivery, dietitian coaching, app access, and peer support:
- Wegovy programme: £149-£249 per month depending on dose
- Mounjaro programme: pricing available on the Second Nature website
- Non-medication programme: from £33/month
heySlim’s starting price is lower, which reflects the difference in what’s included. heySlim provides a prescription with medical oversight. Second Nature’s price includes the prescription plus dietitian coaching, a structured programme, peer support groups, and daily app content.
Who should choose each option
heySlim may suit you if:
- You want affordable, doctor-led access to GLP-1 medication
- You’re comfortable managing your own diet and lifestyle changes
- You prefer doctor consultations over dietitian-led coaching
- You’ve been declined by other providers and want a doctor-led second opinion
- You want a straightforward prescription service without a structured programme
Second Nature may suit you if:
- You want dietitian-led coaching alongside your medication from day one
- Published, peer-reviewed clinical outcomes are important to you
- You want a structured behaviour change programme, not just a prescription
- You value in-app peer support from others at a similar stage
- You want a provider with current NHS weight management partnerships and a long track record
Frequently asked questions
Is heySlim or Second Nature more effective for weight loss?
Second Nature has published peer-reviewed research showing 19.1% average weight loss at 12 months with semaglutide and dietitian-led support.2
heySlim has not published comparable data. Both providers prescribe the same medications, so any difference in outcomes is likely due to the support provided alongside medication.
Is heySlim cheaper than Second Nature?
heySlim’s starting price (from £89/month) is lower than Second Nature’s (from £99/month for Wegovy).
The difference reflects what’s included: heySlim provides a prescription with medical oversight, while Second Nature bundles dietitian coaching, peer support, a structured programme, and daily app content into its price.
If you want medication with minimal support, heySlim is more affordable. If you want a full programme, the additional cost with Second Nature covers that.
What are the reviews on heySlim’s Trustpilot like?
heySlim has a 3.9/5 Trustpilot rating from 82 reviews.4 The review distribution shows a noticeable proportion of 1-star reviews alongside 5-star reviews, which suggests a mixed experience across their patient base.
Second Nature has a 4.5/5 rating from over 7,800 reviews, with a very small proportion of 1-star reviews.
When evaluating any provider, it’s worth reading both positive and negative reviews to understand what went well and what didn’t.
Is heySlim a legitimate service?
heySlim is a UK-based platform that connects patients with UK-registered prescribers. They describe their service as doctor-led, distinguishing it from services using pharmacist prescribers.
As with any online prescriber, it’s worth checking that the clinicians reviewing your case are appropriately registered and that the dispensing pharmacy is GPhC-registered.
Does heySlim offer any behavioural support?
heySlim provides access to your prescribing doctor for questions about nutrition, exercise, and side effects. They also publish blog content on topics like diet plans and switching medications. They don’t offer a structured behaviour change programme, 1-to-1 dietitian coaching, or peer support groups.1
Can I get Wegovy 7.2 mg from both providers?
Yes. Both offer the 7.2 mg dose, approved by the MHRA in January 2026.5 This dose is for patients who have been stable on 2.4mg for at least four weeks and need further weight loss.
Can I switch from heySlim to Second Nature (or vice versa)?
Yes. You can switch providers, though you’ll need a new clinical assessment. If you’re already on a stable dose, you won’t necessarily need to restart from the lowest dose. Both providers can advise on the process.
Does heySlim work with the NHS?
No. heySlim is a private service only. Second Nature has been commissioned by the NHS since 2017, currently across 43 ICBs and Health Boards for weight management and type 2 diabetes prevention.3
What happens when I stop taking medication?
Second Nature builds transition support into its programme, with your dietitian guiding you through reducing or stopping medication. heySlim doesn’t publicly detail a specific aftercare or transition programme.
Research shows that around two-thirds of people regain weight within a year of stopping semaglutide without ongoing behavioural support.6
How new is heySlim?
heySlim is a relatively recent entrant to the UK weight-loss market. Their Trustpilot profile has 82 reviews, suggesting a smaller patient base than more established providers. Second Nature has operated since 2017 with over 7,800 Trustpilot reviews.
A smaller track record isn’t necessarily a negative, but it does mean there’s less publicly available data on long-term patient outcomes and service reliability.
Take home message
heySlim and Second Nature serve different needs. heySlim offers doctor-led access to GLP-1 medication at a lower starting price, with medical oversight and resources, but without a structured behavioural programme.
Second Nature combines medication with dietitian-led coaching, a four-phase behaviour change programme, peer support, and published clinical outcomes.
The Trustpilot profiles reflect this difference in maturity. Second Nature’s 4.5/5 rating from over 7,800 reviews, with very few 1-star reviews, suggests consistent service quality at scale. heySlim’s 3.9/5 rating from 82 reviews, with a higher proportion of 1-star reviews, indicates a more mixed patient experience so far.
If affordable access to medication with doctor oversight is your priority and you’re confident in managing lifestyle changes independently, heySlim may work for you.
If you want a structured programme with published outcomes and professional coaching alongside your medication, Second Nature is built for that.
Second Nature's Mounjaro and Wegovy programmes
Second Nature provides Mounjaro or Wegovy as part of our Mounjaro and Wegovy weight-loss programmes.
Why choose Second Nature over other medication providers, assuming you're eligible?
Because peace of mind matters.
We've had the privilege of working with the NHS for over eight years, helping people across the UK take meaningful steps toward a healthier, happier life.
Our programmes are designed to meet people where they are, whether that means support with weight loss through compassionate one-to-one health coaching, or access to the latest weight-loss medications (like Mounjaro and Wegovy) delivered alongside expert care from a multidisciplinary team of doctors, psychologists, dietitians, and personal trainers.
At the heart of everything we do is a simple belief: real, lasting change comes from building better habits, not relying on quick fixes. We're here to support that change every step of the way.
With over a decade of experience, thousands of lives changed, and a long-standing record of delivering programmes used by the NHS, we believe we're the UK's most trusted weight-loss programme.
We hope to offer you something invaluable: peace of mind, and the support you need to take that first step.
References
- heySlim. Doctor-led Weight Loss.
- Richards, R., et al. (2025). A Remotely Delivered, Semaglutide-Supported Weight Management Program: 12-Month Outcomes. JMIR Formative Research, 9(1), e72577.
- Ross, J.A.D., et al. (2022). Uptake and impact of the English National Health Service digital diabetes prevention programme. BMJ Open Diabetes Research & Care, 10(3), e002736.
- heySlim. Trustpilot reviews.
- Medicines and Healthcare products Regulatory Agency. (2026). Medicines regulator approves up to 7.2mg dose of semaglutide (Wegovy) for patients with obesity only.
- Wilding, J.P.H., et al. (2022). Weight regain and cardiometabolic effects after withdrawal of semaglutide. Diabetes, Obesity and Metabolism, 24(8), 1553-1564.
