When choosing between slimmr and Second Nature for medication-supported weight loss, the most important difference is clinical credibility.
Second Nature has been delivering NHS-commissioned weight-loss services since 2017, with over six years of published clinical outcomes supporting its effectiveness.
In contrast, slimmr launched in 2024 as a newer medication provider focused primarily on drug access with optional add-on support packages.
Both programmes offer weight-loss injections like Mounjaro and Wegovy alongside digital support, but Second Nature’s longer track record and included comprehensive support provides greater peace of mind for patients seeking a clinically-proven approach to sustainable weight loss.
The most significant differences between these programmes are clinical experience, support structure, and value proposition. While slimmr offers competitive medication pricing, Second Nature includes comprehensive behavioural support as standard rather than charging separately for each service.
Lose weight your way and keep it off
GLP-1 medication, expert support, and a programme that fits your life
Key differences between slimmr and Second Nature
Feature
Second Nature
slimmr
NHS Partnership
NHS-commissioned since 2017, used by over half of UK Health Boards
No NHS partnerships
Clinical Evidence
Multiple peer-reviewed publications with proven outcomes
References medication trial data only
Support Structure
Comprehensive support included with medication
Medication-only with paid add-ons
Coaching
UK-registered dietitians and nutritionists included
Optional dietitian support (£150-175 extra)
Programme Options
Both medication-supported and non-medication programmes
Medication-focused only
Trustpilot Rating
4.6/5 from >7,600 reviews
4.8/5 from >100 reviews
Experience
10+ years, 250,000+ patients
Launched 2024
NHS partnership & clinical evidence
Second Nature’s relationship with the NHS sets it apart as the most clinically trusted medication-supported weight loss programme in the UK.
Since 2017, the NHS has commissioned Second Nature to deliver weight loss and type 2 diabetes programmes across the UK, with over half of all UK NHS Health and Care boards using our services.
This NHS partnership ensures robust clinical oversight, data security, and evidence-based approaches that have been tested at scale.
Our published clinical results show participants lost an average of 5.9kg at 12 weeks, with 62.5% achieving at least 5% weight loss by 3 months. For our medication-supported programme, participants lost an average of 6.5kg after 12 weeks.
The National Institute of Health and Care Excellence (NICE) recently announced that Wegovy would be available via digital weight management services provided by Second Nature and three other companies supporting the NHS.
slimmr operates as a newer service without NHS partnerships or published programme-specific clinical data. While they reference clinical trials of the medications themselves, there are no independent studies evaluating slimmr’s specific approach or outcomes.
slimmr was founded by medical professionals with NHS experience, but the service itself hasn’t established the institutional partnerships or published clinical evidence that Second Nature provides.
Programme structure
Both programmes offer medication access with digital support, but their approaches differ significantly in structure and comprehensiveness.
Second Nature’s integrated approach
Our programme is built on a foundation of behavioural science developed through years of NHS collaboration. The approach includes:
Building sustainable habits alongside medication support from day one
Non-restrictive nutrition philosophy that doesn’t require calorie counting
Structured educational content based on clinical evidence
Comprehensive app with food journals, recipes, and progress tracking
Both medication-supported and non-medication options
Focus on post-medication planning from the start
slimmr’s medication-first model
slimmr positions itself as a medication provider with basic included support:
Primary emphasis on GLP-1 medications as the main intervention
Included weekly exercise classes and CBT videos
Some 1:1 coaching and prescriber support included
Optional add-on packages for specialist dietitian or psychology support
No medication-free programme option
The key difference lies in philosophy. Second Nature emphasises habit formation and behavioural change from day one, preparing you for sustainable results even after medication use ends. slimmr focuses primarily on medication provision with supportive elements.
Support & coaching
The quality and accessibility of support can make all the difference when taking weight-loss medications like Mounjaro or Wegovy.
Comprehensive included support at Second Nature
Second Nature provides access to UK-registered dietitians and nutritionists who specialise in supporting members on weight-loss injections as part of your standard programme cost.
Our health coaches are available five days a week via both group and private chat, receiving specific training in side effect management and medication-supported weight loss.
We place you in a small group with others on similar journeys, creating a supportive community where you can share experiences and strategies.
The programme is designed with post-medication life in mind, including focus on sustainable habit formation, personalised transition plans for maintaining results after medication, and ongoing access to support resources even after completing the programme.
slimmr’s tiered support model
slimmr includes basic support with their medication service:
Weekly exercise classes with a qualified trainer
CBT videos focusing on psychological aspects of weight loss
Basic 1:1 coaching and prescriber support included
Regular patient support calls from their team
However, specialist support requires additional payment:
Individual dietitian sessions: £150 per session
Dietitian support group: £175
Individual psychotherapy: Cost varies (£840 for six sessions mentioned in some sources)
slimmr’s approach allows you to choose your level of support, but this means accessing comprehensive guidance requires significant additional investment beyond the medication cost.
Cost comparison
Understanding the total investment helps determine which programme offers better value for your specific needs.
Second Nature pricing:
Mounjaro programme: £229-£299 monthly (increases with higher doses)
Includes all medication, comprehensive app, registered dietitian/nutritionist support, group coaching, and educational content
£100 discount on first month
slimmr pricing:
Wegovy: £189-£299 monthly (increases with dose)
Mounjaro: £189-£249 monthly (increases with dose)
Includes medication, weekly exercise classes, CBT videos, basic coaching, and prescriber support
Additional specialist support costs extra
Total cost comparison for comprehensive support:
If you want the equivalent level of professional guidance at slimmr, the monthly costs would be:
Medication: £189-£299
Plus individual dietitian support: £150+ per session
Plus psychology support: £140+ per session (based on six-session packages)
This means accessing specialist nutrition and psychology support at slimmr could cost £400-600+ monthly, significantly more than Second Nature’s all-inclusive approach.
Patient satisfaction:
Second Nature: 4.6/5 from >7,600 Trustpilot reviews
slimmr: 4.8/5 from >100 reviews
While both services receive excellent reviews, Second Nature’s rating is based on over 75 times more reviews, demonstrating consistent quality at scale.
Take home message
Weight-loss medications like Mounjaro and Wegovy can be transformative when paired with the right support programme. They help silence food-related thoughts and provide the mental space to develop sustainable habits for long-term success.
Choose Second Nature if you value:
Clinical confidence through NHS partnership and published outcomes
Comprehensive support included as standard
Experienced registered dietitians with extensive medication expertise
Proven results with transparent outcome data
Post-medication planning and sustainable habit formation
Consistent quality demonstrated across thousands of patients
Choose slimmr if you prefer:
Lower initial medication costs
Flexibility to add specialist support as needed
Newer service with responsive customer support
Basic included support with optional upgrades
The fundamental difference lies in approach: Second Nature provides comprehensive support as standard, while slimmr operates on a tiered model where specialist guidance costs extra.
For most people seeking medication-supported weight loss, Second Nature’s inclusive approach offers better value and peace of mind.
The combination of NHS validation, clinical evidence, and comprehensive support provides the foundation for lasting success.
If you’re confident in managing your weight loss journey independently and primarily need medication access with basic support, slimmr’s tiered approach may suit your preferences.
Remember that the ultimate goal isn’t just weight loss, but creating a healthier relationship with food and your body that supports long-term wellbeing. This requires more than medication alone.
Lose weight your way and keep it off
GLP-1 medication, expert support, and a programme that fits your life
Second Nature's Mounjaro and Wegovy programmes
Second Nature provides Mounjaro or Wegovy as part of our Mounjaro and Wegovy weight-loss programmes.
Why choose Second Nature over other medication providers, assuming you're eligible?
Because peace of mind matters.
We've had the privilege of working with the NHS for over eight years, helping people across the UK take meaningful steps toward a healthier, happier life.
Our programmes are designed to meet people where they are, whether that means support with weight loss through compassionate one-to-one health coaching, or access to the latest weight-loss medications (like Mounjaro and Wegovy) delivered alongside expert care from a multidisciplinary team of doctors, psychologists, dietitians, and personal trainers.
At the heart of everything we do is a simple belief: real, lasting change comes from building better habits, not relying on quick fixes. We're here to support that change every step of the way.
With over a decade of experience, thousands of lives changed, and a long-standing record of delivering programmes used by the NHS, we believe we're the UK's most trusted weight-loss programme.
We hope to offer you something invaluable: peace of mind, and the support you need to take that first step.
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