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Can you buy Foundayo online in the UK?

Robbie Puddick (RNutr)
Written by

Robbie Puddick (RNutr)

Content and SEO Lead

Dr Rachel Hall
Medically reviewed by

Dr Rachel Hall (MBCHB)

Principal Doctor

14 min read
Last updated August 2026
title

Jump to: Where you can pre-order Foundayo online | Who’s eligible for Foundayo in the UK | How much Foundayo will cost | How buying Foundayo online will work | Foundayo produces an average weight loss of 11.2% | Foundayo is also licensed for keeping weight off | Who Foundayo suits best | How you take Foundayo | Can you get Foundayo on the NHS? | How to buy weight-loss medication safely online | Frequently asked questions | Take home message

You can pre-order Foundayo (orforglipron) online through Second Nature now, if you meet the eligibility criteria, ahead of it going on sale in the coming weeks.

The medicines regulator, the MHRA, approved Foundayo on 10th August 2026, making the UK the first country in Europe to license it.1

Foundayo is a weight-loss tablet taken once a day, with no rules about food, water, or timing, so you can take it at any time of day.1

Second Nature provides Foundayo alongside structured habit-change support from registered dietitians and nutritionists, as we do with the Wegovy pill, Wegovy injections, and Mounjaro.

Important safety information: Foundayo (orforglipron) is a prescription-only medication for managing weight in adults living with obesity, or who are overweight with a weight-related condition. This article is for informational purposes only. Always consult with your healthcare provider before starting, switching, or stopping any weight-loss medication.

Where you can pre-order Foundayo online

Foundayo is available to pre-order through Second Nature. You complete our clinical eligibility assessment, and if you’re approved, your first month’s medication is dispatched as soon as Foundayo becomes available.

Foundayo itself isn’t on sale anywhere yet. It was approved on 10th August 2026, and a newly approved medication usually takes a few weeks to reach pharmacies and online providers.1

The Wegovy pill followed the same pattern. The MHRA approved it on 11th June 2026, and it went on sale around three and a half weeks later, on 6th July.

Once it’s on sale, you’ll also be able to buy it from other regulated providers, including registered online pharmacies, if you meet the eligibility criteria.

Because Foundayo is a prescription-only medication, every regulated provider will ask you to complete a medical assessment before you can place an order.

Our guide to Foundayo covers what it is and how it works in more detail.

Who’s eligible for Foundayo in the UK

The MHRA has licensed Foundayo for adults with a BMI of 30 or above, or a BMI between 27 and 30 with at least one weight-related condition.1

Weight-related conditions include type 2 diabetes, high blood pressure, obstructive sleep apnoea, and high cholesterol.

These are the same criteria as for Wegovy, Mounjaro, and the Wegovy pill, so if you’re already eligible for any of those, you’ll meet the BMI criteria for Foundayo.

The licence also covers weight maintenance, so Foundayo can be prescribed to help you keep weight off after losing it, not only to lose it in the first place.1

Foundayo is also licensed separately to improve blood sugar control in adults living with type 2 diabetes, though this guide covers the weight-management licence.1

A prescriber will also check your medical history and current medications, as Foundayo isn’t suitable for everyone. For example, it’s not recommended during pregnancy or while breastfeeding.

How much Foundayo will cost

Eli Lilly hasn’t announced a UK price for Foundayo, and each provider will set its own monthly cost when it goes on sale.

In the U.S., where Foundayo launched in April 2026, Lilly’s self-pay price ranges from $149 a month at the lowest dose to $349 a month at the highest.

U.S. prices don’t translate directly to the UK. The Wegovy pill costs from £149 a month through Second Nature.

Private Wegovy injections range from around £80 to £150 a month at the starting doses, rising to £269 to £349 at the highest.

When UK prices are announced, check whether the monthly cost includes clinical support or whether that’s charged separately.

How buying Foundayo online will work

The process will be similar across most regulated providers, and it’s the same one used for the Wegovy pill and the injections:

  1. Complete an online eligibility quiz covering your height, weight, medical history, and current medications
  2. A UK-registered clinician reviews your answers to confirm the medication is safe and suitable for you; this process will normally take 1-2 working days
  3. If you’re approved, you place your order and choose your delivery details
  4. Your first month’s medication is dispatched to your chosen address

If you pre-order through Second Nature, you go through the same assessment now, and your order is dispatched once Foundayo goes on sale.

If a provider turns you down, don’t try to work around the decision by giving different answers elsewhere, as the eligibility checks exist to keep you safe. We’d recommend speaking with your GP about your options via the NHS.

Foundayo produces an average weight loss of 11.2%

ATTAIN-1, the main clinical trial of Foundayo, followed 3,127 adults for 72 weeks. Participants were living with obesity, or with overweight plus at least one weight-related condition.2

People taking the highest dose of 36 mg lost an average of 11.2% of their body weight, compared with 2.1% in the placebo group.2

Just over half (54.6%) of the people on this dose lost at least 10% of their body weight.2

You may see a figure of 12.4% quoted elsewhere, which describes the people who stayed on treatment for the full trial. Consider this the higher potential average of the drug if it’s taken every day, and healthy habits are developed alongside it.

The 11.2% includes everyone who joined the trial, whether or not they completed it, and it’s the figure we use across our guides because it better reflects what tends to happen across a real-world group.

Still, these figures are just averages, and the true potential of how much weight we can lose on these medications depends on how well we respond to them and whether we make lifestyle changes alongside them.

The average weight loss of Foundayo may be around 11-12%, but that’s not to say that someone couldn’t lose 20% of their body weight or more (if they needed to) if they made positive lifestyle changes alongside the medication.

Like Wegovy and Mounjaro, Foundayo works on GLP-1, a hormone our body produces in the gut after eating, which reduces hunger and quiets food noise.

Unlike semaglutide, Foundayo isn’t a modified copy of that hormone. It’s a small molecule that mimics the hormone’s action at the same receptor, which is why it can be absorbed like an ordinary tablet.

Comparison of average body weight over time in two clinical trials. In OASIS 4, average body weight on the Wegovy pill (oral semaglutide 25 mg) fell to 86.4% of starting weight by week 64, a 13.6% reduction. In ATTAIN-1, average body weight on Foundayo (orforglipron 36 mg) fell to 88.8% of starting weight by week 72, an 11.2% reduction.

Medication Trial Average weight loss
Foundayo (36 mg, once a day) ATTAIN-1, 72 weeks 11.2%2
Wegovy pill (25 mg, once a day) OASIS 4, 64 weeks 13.6%3
Wegovy injection (2.4 mg, once a week) SURMOUNT-5, 72 weeks 13.7%4
Wegovy injection (7.2 mg, once a week) STEP UP, 72 weeks 20.7%5
Mounjaro injection (15 mg, once a week) SURMOUNT-5, 72 weeks 20.2%4

These trials tested different medications in different groups of people, so the figures are a guide rather than a direct comparison.

Our Wegovy pill vs Foundayo guide compares the two tablets in full.

Foundayo is also licensed for weight maintenance

Foundayo’s UK licence covers weight maintenance as well as weight loss, and a dedicated trial supports that part of it.1

ATTAIN-MAINTAIN followed 376 people who had already lost weight on Mounjaro or Wegovy injections, and switched them to either Foundayo or a placebo for a year.6

People who switched to Foundayo kept around 75 to 79% of the weight they’d lost. People who switched to a placebo kept around 38 to 49%.6

Our guide to oral GLP-1s for weight maintenance covers this evidence in more detail.

Who Foundayo suits best

Mounjaro and the 7.2 mg Wegovy injection produce the biggest average weight losses in trials, at 20.2% and 20.7%.4,5

But many people don’t need to lose 20% of their body weight.

In our experience, many people need extra help with their appetite to lose 10 to 15% of their body weight, and to keep it off in the long term.

If you’re in that group, and you’d rather take a tablet at any time of day than have a weekly injection or follow the Wegovy pill’s morning fasting routine, Foundayo is likely to suit you.

Foundayo is also an option for people coming off Mounjaro or Wegovy injections. The ATTAIN-MAINTAIN results above suggest it can help you keep off most of the weight you’ve lost.6

If the largest possible weight loss is your priority, Mounjaro or the 7.2 mg Wegovy injection may suit you better.

If you want the most effective tablet, the Wegovy pill produced more average weight loss than Foundayo (13.6% versus 11.2%), though it comes with strict rules about food and water timing.2,3

Second Nature has worked with the NHS since 2017, and offers Foundayo alongside its structured habit-change programme. Pre-order Foundayo here, and a clinician will review your answers before your order is confirmed.

How you take Foundayo

Foundayo is taken once a day, at any time of day, with or without food.1

This is the main practical difference from the Wegovy pill, which has to be taken when you wake up, on an empty stomach, with no more than half a glass of water, followed by a 30-minute wait before eating or drinking anything else.

Semaglutide is a peptide, which the stomach breaks down in the same way it breaks down protein in food, so the Wegovy pill only works if it’s absorbed on an empty stomach.

Foundayo is a small molecule rather than a peptide, so it passes through the stomach without being broken down and is absorbed like an ordinary tablet.

Storage is simpler, too. The tablets are kept at room temperature, while the injection pens need to be refrigerated before first use.

Treatment starts at 0.8 mg a day and increases through 2.5 mg, 5.5 mg, 9 mg, and 14.5 mg up to the highest dose of 17.2 mg, with at least a month at each level.1

The tablet strengths look different from the doses reported in the trials because the trials used an earlier capsule form of the drug. The 17.2 mg tablet delivers the same dose as the trial’s 36 mg capsule.

The most common side effects are gut-related, including nausea, constipation, diarrhoea, vomiting, indigestion, and abdominal pain.1

In ATTAIN-1, between 5.3% and 10.3% of people taking Foundayo stopped treatment because of side effects, depending on the dose, compared with 2.7% in the placebo group.2

Serious side effects are rare. Contact your GP or prescriber urgently if you have severe stomach pain that doesn’t settle, as this can be a sign of pancreatitis (inflammation of the pancreas).

Can you get Foundayo on the NHS?

No, Foundayo isn’t available on the NHS, as it needs to be approved by NICE before it can be provided on the NHS.1

Approval by the MHRA and NHS funding are two separate decisions, made by two different organisations.

NICE, the body that decides which medications the NHS funds, now needs to assess whether Foundayo represents good value.1 There’s no confirmed timeline for that decision.

Wegovy injections are already available through NHS specialist weight management services, and Mounjaro through GP practices in a phased rollout, both for people who meet stricter criteria.

Our guide to getting Wegovy on the NHS covers the current criteria in full.

How to buy weight-loss medication safely online

Foundayo is a prescription-only medication, so any website offering it without a medical assessment is selling it illegally.

Until it officially goes on sale in the UK, regulated providers can take pre-orders but can’t dispatch the medication, so be cautious of any site claiming to have Foundayo in stock today.

Once it’s available, before you order from any provider, check that:

  • They ask about your height, weight, medical history, and medications before prescribing
  • The clinician prescribing your medication is registered in the UK
  • The pharmacy dispensing your medication is registered with the General Pharmaceutical Council (the regulator for UK pharmacies)
  • The price is close to what other regulated providers charge

An unusually low price, no medical questions, or sales through social media are all signs of an unregulated seller, and a higher risk of counterfeit medication.

Frequently asked questions

When will Foundayo be available in the UK?

The MHRA approved Foundayo on 10th August 2026, and it’s expected to go on sale through private providers in the coming weeks.1

You can pre-order it through Second Nature now, and your order will be dispatched once it goes on sale.

Can you pre-order Foundayo in the UK?

Yes, Second Nature is taking pre-orders for Foundayo now.

You complete a medical assessment first, and if you’re approved, your first month’s medication is dispatched as soon as Foundayo goes on sale.

Do you need a prescription for Foundayo?

Yes, Foundayo is a prescription-only medication in the UK.

A UK-registered prescriber must confirm that you meet the eligibility criteria before a pharmacy can dispense it.

Can you buy Foundayo over the counter?

No, pharmacies can’t sell Foundayo without a prescription. This applies equally to high-street and online pharmacies.

How much will Foundayo cost in the UK?

There’s no UK price yet, and each provider will set its own monthly cost when it goes on sale.

In the U.S., Lilly’s self-pay price ranges from $149 to $349 a month depending on the dose.

Is Foundayo a GLP-1?

Yes, Foundayo works on the same GLP-1 system as Wegovy and Mounjaro, reducing hunger and quieting food noise.

It’s a small molecule rather than a copy of the GLP-1 hormone, which is why it can be absorbed as an ordinary tablet without any food or water rules.

What time of day should you take Foundayo?

You can take Foundayo at any time of day, with or without food.1

Many people find it easiest to take a daily tablet alongside an existing routine, such as brushing your teeth, so it becomes automatic.

Is Foundayo the same as Mounjaro?

No. Both are made by Eli Lilly, but Mounjaro (tirzepatide) is a weekly injection that mimics two hormones, while Foundayo is a daily tablet that mimics one, GLP-1.

Mounjaro also produced more average weight loss in trials: 20.2% compared with Foundayo’s 11.2%.2,4

Is Foundayo better than the Wegovy pill?

The Wegovy pill produced more average weight loss in its main trial: 13.6%, compared with Foundayo’s 11.2%.2,3

Foundayo has no rules about food, water, or timing (it can be taken any time of day), while the Wegovy pill must be taken on an empty stomach with a 30-minute wait before eating.

Our Wegovy pill vs Foundayo guide compares the two in full.

Can you switch from the Wegovy pill to Foundayo?

Yes, once Foundayo is on sale, you can switch with your prescriber’s agreement, for example if the empty-stomach routine doesn’t suit you.

The two tablets haven’t been directly compared in a trial. In OASIS 4, the Wegovy pill produced an average weight loss of 13.6%; in ATTAIN-1, Foundayo produced 11.2%.2,3

Can you switch to Foundayo from Mounjaro or Wegovy injections?

Yes, once it’s on sale, you’ll be able to switch if you and your prescriber decide it suits you.

In the ATTAIN-MAINTAIN trial, people who switched to Foundayo after losing weight on the injections kept around 75 to 79% of the weight they’d lost.6

Is Foundayo available on the NHS?

No, Foundayo will only be available privately at first.1

NICE would need to recommend it before the NHS could fund it, and there’s no confirmed timeline for that decision.

What happens if you stop taking Foundayo?

Stopping a GLP-1 medication often leads to weight regain if you stop suddenly and haven’t developed the habits needed to maintain the weight loss.

In the STEP 4 trial, people who stopped the 2.4 mg Wegovy injection regained an average of 6.9% of their body weight over the following 48 weeks.7

We recommend coming off any weight-loss medication slowly, by gradually reducing the dose, and ensuring you have habits in place to manage hunger naturally.

Our free weight regain prevention planner can help you plan this.

Take home message

Foundayo was approved by the MHRA on 10th August 2026, and you can pre-order it online through Second Nature now if you meet the eligibility criteria.

Foundayo produced an average weight loss of 11.2% in its main trial, below the Wegovy pill’s 13.6% and the 20% or more from the highest-dose injections.

Unlike the Wegovy pill, it can be taken at any time of day with no food or water rules, and its licence covers keeping weight off as well as losing it.

That combination suits people who want a moderate amount of weight loss with fewer rules around taking it, or who want support maintaining their weight after Mounjaro or Wegovy injections.

The research suggests you’re more likely to avoid weight regain when weight-loss medication is combined with structured habit-change support than when it’s prescribed on its own.

Second Nature’s medication-supported programme pairs the medication with habit-change support from registered dietitians and nutritionists, built around a balanced plate of vegetables, protein, complex carbohydrates, and healthy fats.

In a study published in JMIR Formative Research, members of the programme lost an average of 19.1% of their body weight at 12 months, with 77.7% losing at least 10%.8

Second Nature's Mounjaro and Wegovy programmes

Second Nature provides Mounjaro or Wegovy as part of our Mounjaro and Wegovy weight-loss programmes.

Why choose Second Nature over other medication providers, assuming you're eligible?

Because peace of mind matters.

We've had the privilege of working with the NHS for over eight years, helping people across the UK take meaningful steps toward a healthier, happier life.

Our programmes are designed to meet people where they are, whether that means support with weight loss through compassionate one-to-one health coaching, or access to the latest weight-loss medications (like Mounjaro and Wegovy) delivered alongside expert care from a multidisciplinary team of doctors, psychologists, dietitians, and personal trainers.

At the heart of everything we do is a simple belief: real, lasting change comes from building better habits, not relying on quick fixes. We're here to support that change every step of the way.

With over a decade of experience, thousands of lives changed, and a long-standing record of delivering programmes used by the NHS, we believe we're the UK's most trusted weight-loss programme.

We hope to offer you something invaluable: peace of mind, and the support you need to take that first step.

References

  1. Medicines and Healthcare products Regulatory Agency. (2026). UK first in Europe to authorise orforglipron for weight management and type 2 diabetes.
  2. Wharton, S., Aronne, L.J., Stefanski, A., et al. (2025). Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity Treatment. New England Journal of Medicine, 393(18), 1796-1806. (ATTAIN-1 trial)
  3. Wharton, S., Lingvay, I., Bogdanski, P., et al. (2025). Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity. New England Journal of Medicine, 393(11), 1077-1087. (OASIS 4 trial)
  4. Aronne, L.J., Horn, D.B., le Roux, C.W., et al. (2025). Tirzepatide as Compared with Semaglutide for the Treatment of Obesity. New England Journal of Medicine, 393(1), 26-36. (SURMOUNT-5 trial)
  5. Wharton, S., Freitas, P., Hjelmesæth, J., et al. (2025). Once-weekly semaglutide 7.2 mg in adults with obesity (STEP UP): a randomised, controlled, phase 3b trial. Lancet Diabetes & Endocrinology, 13(11), 949-963. (STEP UP trial)
  6. Aronne, L.J., Horn, D.B., le Roux, C.W., et al. (2026). Orforglipron for maintenance of body weight reduction: the double-blind, randomized phase 3b ATTAIN-MAINTAIN trial. Nature Medicine, 32(7), 2679-2687. (ATTAIN-MAINTAIN trial)
  7. Rubino, D., Abrahamsson, N., Davies, M., et al. (2021). Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial. JAMA, 325(14), 1414-1425. (STEP 4 trial)
  8. Richards, R., Whitman, M., Wren, G., et al. (2025). A Remotely Delivered GLP-1RA-Supported Specialist Weight Management Program in Adults Living With Obesity: Retrospective Service Evaluation. JMIR Formative Research, 9(1), e72577.
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