Second Nature logo

US

Interested in our medication-supported weight-loss programme?

Weight-Loss Injections

GLP-1s are a new class of weight loss injections proven to help people achieve significant weight loss by reducing appetite and improving insulin function. Learn what GLP-1s are, how they work, whether you should use them, and the possible side effects.
Can you get retatrutide on the NHS?

Weight-Loss Injections

Can you get retatrutide on the NHS?

No, retatrutide isn't on the NHS as of 2026. We explain when it might be, who'll be eligible, and the MHRA-approved alternatives available now.

Can you buy retatrutide online safely in the UK?

Weight-Loss Injections

Can you buy retatrutide online safely in the UK?

No, retatrutide isn't legally available to buy in the UK in 2026. We explain why, the risks of online sellers, and MHRA-approved alternatives.

What is retatrutide?

Weight-Loss Injections

What is retatrutide?

Retatrutide is a new weight-loss injection made by Eli Lilly. The drug leads to an average of 24% weight loss and may be available by 2028.

How long can you stay on Mounjaro?

Weight-Loss Injections

How long can you stay on Mounjaro?

There's no fixed time limit on Mounjaro privately. Most reach their goal in 1-2 years, then continue, step down, or come off with habit support.

How long can I stay on Wegovy?

Weight-Loss Injections

How long can I stay on Wegovy?

You can stay on Wegovy long-term if it's medically appropriate. Most reach their goal in 14-18 months, then continue, step down, or transition off.

Can you take Mounjaro with levothyroxine?

Weight-Loss Injections

Can you take Mounjaro with levothyroxine?

Yes, you can take Mounjaro with levothyroxine. Learn how to time both medications, monitor TSH, and adjust your dose as you lose weight.

Can you take Mounjaro if you don’t have a gallbladder?

Weight-Loss Injections

Can you take Mounjaro if you don’t have a gallbladder?

You can take Mounjaro without a gallbladder if your BMI is >27. Expert guidance on safety, managing side effects, & preventing post-surgery diarrhoea.

Can you take Mounjaro with hypothyroidism?

Weight-Loss Injections

Can you take Mounjaro with hypothyroidism?

You can take Mounjaro with hypothyroidism when thyroid levels are well-controlled. Learn about timing, monitoring, & safety considerations.

Can you take Mounjaro if you have anxiety?

Weight-Loss Injections

Can you take Mounjaro if you have anxiety?

You can take Mounjaro if you have anxiety but you should continue to take your anti-anxiety medications and ongoing therapy, like CBT. Find out more here.

Can you take Mounjaro if you have osteoporosis?

Weight-Loss Injections

Can you take Mounjaro if you have osteoporosis?

You can take Mounjaro if you have osteoporosis, but you must lose weight slowly, eat a protein-rich diet, and exercise 2-3 times a week. Find out more.

Make losing weight feel Second Nature

The first step on your Second Nature journey is to take our health quiz.

Hand holding phone

As seen on

The GuardianThe TimesChannel 4The Sunday TelegraphEvening StandardMetro