Weight-loss medications
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Weight-loss medications
Free UK eligibility checker for Mounjaro and Wegovy: BMI 30+ private, BMI 40+ NHS (TA1026), or BMI 27+ with a condition. Ethnic thresholds applied.
Wegovy compatibility
You can take Wegovy with osteoarthritis. The STEP 9 trial showed that Wegovy supported a reduction in knee pain and improved daily function.
Mounjaro compatibility
You can take Mounjaro alongside propranolol. The main considerations are added blood pressure effects and hidden low blood sugar warning signs.
Weight-loss medications
ATTAIN-MAINTAIN trial: people who switched from Mounjaro or Wegovy injections to Foundayo kept 75-79% of their weight loss. Not yet approved in the UK.
Weight-loss medications
The Wegovy pill (oral semaglutide 25 mg) is the first GLP-1 pill approved for weight loss. FDA-approved in the U.S., UK approved in June 2026.
Weight-loss medications
Wegovy pill vs Foundayo: 13.6% vs 11.2% average weight loss in trials. Wegovy pill needs an empty stomach; Foundayo can be taken any time.
Weight-loss medications
Three oral GLP-1 weight-loss pills compared. Wegovy pill (13.6%) and Foundayo (11.2%) expected in UK late 2026 and 2027; Rybelsus available now for type 2.
Weight-loss medications
Retatrutide produced 28.7% weight loss in trials vs Wegovy 7.2 mg's 20.7%. Retatrutide isn't UK-approved yet; Wegovy is the current option.
Weight-loss medications
Retatrutide's main side effects in trials: nausea (43%), heart rate increase of ~6.7 bpm, and dysesthesia (20.9%) at the 12 mg dose. Not yet UK-approved.