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Interested in our medication-supported weight-loss programme?

Weight-loss medications

Evidence-based guidance on weight-loss medications including GLP-1 receptor agonists like Wegovy, Ozempic, and Mounjaro. Find reliable information on efficacy, side effects, NHS availability, and how these medications work as part of a balanced approach to weight loss. Our content is developed by healthcare professionals and nutritionists to support informed decisions about medication-assisted weight loss in the UK.
Does your appetite come back after stopping Mounjaro?

Weight-loss medications

Does your appetite come back after stopping Mounjaro?

Appetite returns after stopping Mounjaro, but weight regain isn't inevitable. Developing healthy habits while on the medication can help to manage hunger.

Can you take Mounjaro with heart rhythm medications?

Mounjaro compatibility

Can you take Mounjaro with heart rhythm medications?

Yes, you can take Mounjaro with most heart rhythm medications. Learn how it interacts with beta-blockers, digoxin, amiodarone, and more.

Can you take Mounjaro with atrial fibrillation?

Mounjaro compatibility

Can you take Mounjaro with atrial fibrillation?

Yes, you can take Mounjaro if you have atrial fibrillation. Learn how it affects heart rate, anticoagulants, and AF burden, plus what to watch for.

Can you take Mounjaro if you have lupus?

Weight-loss medications

Can you take Mounjaro if you have lupus?

Yes, you can take Mounjaro if you have lupus. Learn how it interacts with hydroxychloroquine, steroids, and other SLE medications, plus safety tips.

Can you take Mounjaro with prediabetes?

Weight-loss medications

Can you take Mounjaro with prediabetes?

Mounjaro isn't licensed for prediabetes alone, but may be an option if you also meet the BMI criteria. Plus metformin, the NHS DPP, and lifestyle tips.

Why exercise feels harder on Mounjaro (and how to make it work for you)

Weight-loss medications

Why exercise feels harder on Mounjaro (and how to make it work for you)

Free, personalised Mounjaro exercise planner. Build a week-by-week plan around your dose day, side effects, and fitness level. UK, nutritionist-written.

Wegovy exercise plan: Managing nausea, heart rate changes, and energy

Weight-loss medications

Wegovy exercise plan: Managing nausea, heart rate changes, and energy

Free, personalised Wegovy exercise planner. Train safely despite nausea, fatigue, and changes in heart rate. UK, nutritionist-written guide.

Can you take Mounjaro with anticoagulants like apixaban or rivaroxaban?

Mounjaro compatibility

Can you take Mounjaro with anticoagulants like apixaban or rivaroxaban?

You can take Mounjaro (tirzepatide) if you're on anticoagulants like apixaban or rivaroxaban, but you'll need closer monitoring of your clotting levels.

Can you take Mounjaro if you have epilepsy?

Weight-loss medications

Can you take Mounjaro if you have epilepsy?

Can you take Mounjaro with epilepsy? Yes, with medical supervision. Research shows GLP-1 medications may reduce seizure risk by 24%. UK expert guidance.

Can you take Mounjaro if you have chronic kidney disease (CKD)?

Weight-loss medications

Can you take Mounjaro if you have chronic kidney disease (CKD)?

You can take Mounjaro with chronic kidney disease (CKD), but only under medical supervision. Second Nature doesn't accept patients with CKD. Find out more.

Make losing weight feel Second Nature

The first step on your Second Nature journey is to take our health quiz.

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