US
Weight-loss medications
Evidence-based guidance on weight-loss medications including GLP-1 receptor agonists like Wegovy, Ozempic, and Mounjaro. Find reliable information on efficacy, side effects, NHS availability, and how these medications work as part of a balanced approach to weight loss. Our content is developed by healthcare professionals and nutritionists to support informed decisions about medication-assisted weight loss in the UK.
Weight-loss medications
Why exercise feels harder on Mounjaro (and how to make it work for you)
Free, personalised Mounjaro exercise planner. Build a week-by-week plan around your dose day, side effects, and fitness level. UK, nutritionist-written.
Weight-loss medications
Wegovy exercise plan: Managing nausea, heart rate changes, and energy
Free, personalised Wegovy exercise planner. Train safely despite nausea, fatigue, and changes in heart rate. UK, nutritionist-written guide.
Mounjaro compatibility
Can you take Mounjaro with anticoagulants like apixaban or rivaroxaban?
You can take Mounjaro (tirzepatide) if you're on anticoagulants like apixaban or rivaroxaban, but you'll need closer monitoring of your clotting levels.
Weight-loss medications
Can you take Mounjaro if you have epilepsy?
Can you take Mounjaro with epilepsy? Yes, with medical supervision. Research shows GLP-1 medications may reduce seizure risk by 24%. UK expert guidance.
Weight-loss medications
Can you take Mounjaro if you have chronic kidney disease (CKD)?
You can take Mounjaro with chronic kidney disease (CKD), but only under medical supervision. Second Nature doesn't accept patients with CKD. Find out more.
Wegovy compatibility
Can I take painkillers while on Wegovy?
Can you take painkillers with Wegovy? Yes. Paracetamol is safest, NSAIDs need food, and codeine increases constipation risk. Full guide with UK guidance.
Wegovy compatibility
Can you take Wegovy with anxiety?
Yes, there's no interaction between Wegovy and anxiety medications like SSRIs. How to tell Wegovy side effects apart from anxiety symptoms.
Wegovy compatibility
Can you take Wegovy while on statins?
Yes, no interaction between Wegovy and statins. The SELECT trial showed a 20% reduction in cardiovascular events on top of statin therapy.
Weight-loss medications
GLP-1 muscle and protein planner: maintain muscle while losing weight
Without resistance training, up to 40% of weight lost on GLP-1 medications can be muscle. Get a free personalised protein and exercise plan.
Weight-loss medications
Foundayo (orforglipron): what it is, how it works, and when it’s coming to the UK
Foundayo (orforglipron) is a daily GLP-1 pill for weight loss with no fasting requirements. FDA-approved April 2026. Average weight loss 11.2% at 72 weeks.
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