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Interested in our medication-supported weight-loss programme?

Weight-loss medications

Evidence-based guidance on weight-loss medications including GLP-1 receptor agonists like Wegovy, Ozempic, and Mounjaro. Find reliable information on efficacy, side effects, NHS availability, and how these medications work as part of a balanced approach to weight loss. Our content is developed by healthcare professionals and nutritionists to support informed decisions about medication-assisted weight loss in the UK.
Can you take Mounjaro every other week?

Weight-loss medications

Can you take Mounjaro every other week?

Can't afford weekly Mounjaro? Learn why taking it every other week isn't NHS-recommended and what safe alternatives exist for managing costs effectively.

Can you take Wegovy without a gallbladder?

Wegovy compatibility

Can you take Wegovy without a gallbladder?

You can take Wegovy after gallbladder removal. Learn how it prevents post-surgery weight gain, digestive management tips, and monitoring guidelines.

Can you take Wegovy if you have gallstones?

Wegovy compatibility

Can you take Wegovy if you have gallstones?

Can you take Wegovy with gallstones? Yes, but monitor closely. Learn about the risk, safety guidelines, and how to minimise complications during treatment.

Can you take Wegovy with hypothryoidism?

Weight-loss medications

Can you take Wegovy with hypothryoidism?

You can take Wegovy (semaglutide) if you have an underactive thyroid (hypothyroidism) and your BMI is over 27 as there are no known interactions.

Can you microdose Mounjaro? Understanding the clinical guidelines

Weight-loss medications

Can you microdose Mounjaro? Understanding the clinical guidelines

Discover why microdosing Mounjaro isn't recommended by medical experts. Learn about the risks of it and safer alternatives for managing side effects.

Finding your optimal Mounjaro dose: Is lower better?

Weight-loss medications

Finding your optimal Mounjaro dose: Is lower better?

Find your ideal Mounjaro dose. Learn when lower doses work best, signs of optimal response, and how to discuss options with your provider.

Mounjaro alternatives: Your complete guide to weight loss options in 2025

Weight-loss medications

Mounjaro alternatives: Your complete guide to weight loss options in 2025

Wegovy (semaglutide) is currently the best alternative to Mounjaro, with clinical trials showing 13-19% average weight loss compared to Mounjaro's 20%.

How to switch from Mounjaro to Wegovy safely

Weight-loss medications

How to switch from Mounjaro to Wegovy safely

You can switch from Mounjaro (tirzepatide) to Wegovy (semaglutide) under medical supervision. Learn how to do it safely without impacting progress here.

Why has the Mounjaro price increased in the UK?

Weight-loss medications

Why has the Mounjaro price increased in the UK?

Eli Lilly's Mounjaro price increase: UK impact, NHS vs private patients, & affordable alternatives. Second Nature now offers a Wegovy programme.

Can Mounjaro cause heavy bleeding?

Side effects

Can Mounjaro cause heavy bleeding?

Mounjaro can cause heavier periods and cycle changes due to rapid weight loss affecting hormones. Learn what to expect and how to manage menstrual changes.

Make losing weight feel Second Nature

The first step on your Second Nature journey is to take our health quiz.

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