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Interested in our medication-supported weight-loss programme?

Weight-loss medications

Evidence-based guidance on weight-loss medications including GLP-1 receptor agonists like Wegovy, Ozempic, and Mounjaro. Find reliable information on efficacy, side effects, NHS availability, and how these medications work as part of a balanced approach to weight loss. Our content is developed by healthcare professionals and nutritionists to support informed decisions about medication-assisted weight loss in the UK.
Can you take Wegovy with metformin?

Wegovy compatibility

Can you take Wegovy with metformin?

Yes, you can take Wegovy (semaglutide) with metformin. Research has shown that the combination can lead to improved blood sugar control and weight loss.

Can you take Wegovy with sertraline (Zoloft)?

Wegovy compatibility

Can you take Wegovy with sertraline (Zoloft)?

You can take Wegovy with sertraline as no known interactions exist between the medications. Learn about safety, monioring, and side effects here.

Can you take Wegovy with fatty liver disease?

Wegovy compatibility

Can you take Wegovy with fatty liver disease?

You can take Wegovy if you have fatty liver disease as studies have shown that it can significantly improve the condition and lower liver fat levels.

Can you take Wegovy with high blood pressure?

Wegovy compatibility

Can you take Wegovy with high blood pressure?

Wegovy can lower blood pressure by approximately 5 mmHg and is safe to take if you have high blood pressure. Learn how to monitor BP while on Wegovy here.

Should you fast on Wegovy?

Weight-loss medications

Should you fast on Wegovy?

Fasting on Wegovy increases muscle loss and nutrient deficiencies. Learn why 3 balanced meals a day supports weight loss on semaglutide.

Should you fast while on Mounjaro?

Weight-loss medications

Should you fast while on Mounjaro?

Fasting on Mounjaro increases the risk of muscle loss and nutrient deficiencies. Learn why 3 protein-rich meals a day supports weight loss on Mounjaro.

Wegovy diet plan for weight loss and muscle maintenance

Weight-loss medications

Wegovy diet plan for weight loss and muscle maintenance

Practical Wegovy diet plan with protein-rich meals, portion guides and tips to manage side effects while maximising weight loss and muscle maintenance.

7-day Mounjaro meal plan | Dietitian approved meal plan for weight loss

Weight-loss medications

7-day Mounjaro meal plan | Dietitian approved meal plan for weight loss

Our 7-day Mounjaro meal plan includes protein-rich recipes, side effect management tips, and practical portion guidance. Click here to download it now.

Coming off of Mounjaro: how to stop safely and maintain weight loss

Weight-loss medications

Coming off of Mounjaro: how to stop safely and maintain weight loss

Learn how to safely come off Mounjaro and maintain weight loss. 59% who taper slowly keep weight off. Expert guide with proven strategies.

Wegovy exercise plan: Managing nausea, heart rate changes, and energy

Weight-loss medications

Wegovy exercise plan: Managing nausea, heart rate changes, and energy

Exercise feels harder on Wegovy due to fatigue. Discover practical strategies for working out safely, managing nausea, & building fitness gradually.

Make losing weight feel Second Nature

The first step on your Second Nature journey is to take our health quiz.

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