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Why GLP-1 medications work better for some people than others

Current Health

Why GLP-1 medications work better for some people than others

A Nature study of 27,885 people identified gene variants that predict GLP-1 weight loss and nausea risk, including one specific to Mounjaro users.

Can you take Wegovy with anxiety?

Wegovy compatibility

Can you take Wegovy with anxiety?

Yes, there's no interaction between Wegovy and anxiety medications like SSRIs. How to tell Wegovy side effects apart from anxiety symptoms.

Can you take Wegovy while on statins?

Wegovy compatibility

Can you take Wegovy while on statins?

Yes, no interaction between Wegovy and statins. The SELECT trial showed a 20% reduction in cardiovascular events on top of statin therapy.

GLP-1 muscle and protein planner: maintain muscle while losing weight

Weight-loss medications

GLP-1 muscle and protein planner: maintain muscle while losing weight

Without resistance training, up to 40% of weight lost on GLP-1 medications can be muscle. Get a free personalised protein and exercise plan.

Foundayo (orforglipron): what it is, how it works, and when it’s coming to the UK

Weight-loss medications

Foundayo (orforglipron): what it is, how it works, and when it’s coming to the UK

Foundayo (orforglipron) is a daily GLP-1 pill for weight loss with no fasting requirements. FDA-approved April 2026. Average weight loss 11.2% at 72 weeks.

Mounjaro and Wegovy week-by-week: what to expect at every stage

Weight-loss medications

Mounjaro and Wegovy week-by-week: what to expect at every stage

What to expect on Mounjaro & Wegovy week-by-week, based on clinical data. Includes weight loss, dose schedules, plateau advice, & an interactive timeline.

Can you take Mounjaro if you have anxiety?

Weight-Loss Injections

Can you take Mounjaro if you have anxiety?

You can take Mounjaro if you have anxiety but you should continue to take your anti-anxiety medications and ongoing therapy, like CBT. Find out more here.

Can you take Mounjaro if you have osteoporosis?

Weight-Loss Injections

Can you take Mounjaro if you have osteoporosis?

You can take Mounjaro if you have osteoporosis, but you must lose weight slowly, eat a protein-rich diet, and exercise 2-3 times a week. Find out more.

Can you take Mounjaro if you have ADHD?

Weight-Loss Injections

Can you take Mounjaro if you have ADHD?

You can take Mounjaro if you have ADHD as it may offer several benefits to support the unique challenges people with ADHD face when trying to lose weight.

Can you take Mounjaro with depression?

Weight-Loss Injections

Can you take Mounjaro with depression?

You can take Mounjaro if you're living with depression. Emerging research suggests it can lower depressive symtpoms and improve quality of life.

Make losing weight feel Second Nature

The first step on your Second Nature journey is to take our health quiz.

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