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Interested in our medication-supported weight-loss programme?

Weight-loss medications

Evidence-based guidance on weight-loss medications including GLP-1 receptor agonists like Wegovy, Ozempic, and Mounjaro. Find reliable information on efficacy, side effects, NHS availability, and how these medications work as part of a balanced approach to weight loss. Our content is developed by healthcare professionals and nutritionists to support informed decisions about medication-assisted weight loss in the UK.
Can you take Wegovy if you have cardiovascular disease (CVD)?

Wegovy compatibility

Can you take Wegovy if you have cardiovascular disease (CVD)?

Yes, you can take Wegovy if you have cardiovascular disease. In the SELECT trial it cut heart attack and stroke risk by 20%.

Can you take Wegovy if you have atrial fibrillation?

Wegovy compatibility

Can you take Wegovy if you have atrial fibrillation?

You can take Wegovy if you have atrial fibrillation, with cardiology input. A SELECT trial analysis found 27% lower AF recurrence on semaglutide.

Can you get Ozempic on the NHS?

Weight-loss medications

Can you get Ozempic on the NHS?

Ozempic is only available on the NHS for type 2 diabetes, not weight loss. Wegovy and Mounjaro are the UK's licensed weight-loss injections.

7-day Mounjaro meal plan | Dietitian approved meal plan for weight loss

Weight-loss medications

7-day Mounjaro meal plan | Dietitian approved meal plan for weight loss

Our 7-day Mounjaro meal plan includes protein-rich recipes, side effect management tips, and practical portion guidance. Click here to download it now.

GLP-1 BMI calculator: Am I eligible for weight-loss injections in the UK?

Weight-loss medications

GLP-1 BMI calculator: Am I eligible for weight-loss injections in the UK?

Free UK eligibility checker for Mounjaro and Wegovy: BMI 30+ private, BMI 40+ NHS (TA1026), or BMI 27+ with a condition. Ethnic thresholds applied.

Can you take Wegovy with osteoarthritis?

Wegovy compatibility

Can you take Wegovy with osteoarthritis?

You can take Wegovy with osteoarthritis. The STEP 9 trial showed that Wegovy supported a reduction in knee pain and improved daily function.

Wegovy pill vs Wegovy injection: which works better, and which is right for you?

Weight-loss medications

Wegovy pill vs Wegovy injection: which works better, and which is right for you?

The Wegovy injection produced an average weight loss of 14.9% in trials vs 13.6% for the Wegovy pill. The pill isn't yet available in the UK.

Can you take Mounjaro with propranolol?

Mounjaro compatibility

Can you take Mounjaro with propranolol?

You can take Mounjaro alongside propranolol. The main considerations are added blood pressure effects and hidden low blood sugar warning signs.

Can oral weight-loss medications help you maintain weight loss after Mounjaro or Wegovy?

Weight-loss medications

Can oral weight-loss medications help you maintain weight loss after Mounjaro or Wegovy?

ATTAIN-MAINTAIN trial: people who switched from Mounjaro or Wegovy injections to Foundayo kept 75-79% of their weight loss. Not yet approved in the UK.

The Wegovy pill: what it is, how it works, and when it’s coming to the UK

Weight-loss medications

The Wegovy pill: what it is, how it works, and when it’s coming to the UK

The Wegovy pill (oral semaglutide 25 mg) is the first GLP-1 pill approved for weight loss. FDA-approved in the U.S., UK availability is expected late 2026.

Make losing weight feel Second Nature

The first step on your Second Nature journey is to take our health quiz.

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