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Interested in our medication-supported weight-loss programme?

Weight-loss medications

Evidence-based guidance on weight-loss medications including GLP-1 receptor agonists like Wegovy, Ozempic, and Mounjaro. Find reliable information on efficacy, side effects, NHS availability, and how these medications work as part of a balanced approach to weight loss. Our content is developed by healthcare professionals and nutritionists to support informed decisions about medication-assisted weight loss in the UK.
Can I take painkillers while on Wegovy?

Wegovy compatibility

Can I take painkillers while on Wegovy?

Can you take painkillers with Wegovy? Yes. Paracetamol is safest, NSAIDs need food, and codeine increases constipation risk. Full guide with UK guidance.

Can you take Wegovy with anxiety?

Wegovy compatibility

Can you take Wegovy with anxiety?

Yes, there's no interaction between Wegovy and anxiety medications like SSRIs. How to tell Wegovy side effects apart from anxiety symptoms.

Can you take Wegovy while on statins?

Wegovy compatibility

Can you take Wegovy while on statins?

Yes, no interaction between Wegovy and statins. The SELECT trial showed a 20% reduction in cardiovascular events on top of statin therapy.

GLP-1 muscle and protein planner: maintain muscle while losing weight

Weight-loss medications

GLP-1 muscle and protein planner: maintain muscle while losing weight

Without resistance training, up to 40% of weight lost on GLP-1 medications can be muscle. Get a free personalised protein and exercise plan.

Foundayo (orforglipron): what it is, how it works, and when it’s coming to the UK

Weight-loss medications

Foundayo (orforglipron): what it is, how it works, and when it’s coming to the UK

Foundayo (orforglipron) is a daily GLP-1 pill for weight loss with no fasting requirements. FDA-approved April 2026. Average weight loss 11.2% at 72 weeks.

Mounjaro and Wegovy week-by-week: what to expect at every stage

Weight-loss medications

Mounjaro and Wegovy week-by-week: what to expect at every stage

What to expect on Mounjaro & Wegovy week-by-week, based on clinical data. Includes weight loss, dose schedules, plateau advice, & an interactive timeline.

Is there a Mounjaro pill? What you need to know

Weight-loss medications

Is there a Mounjaro pill? What you need to know

There's no Mounjaro pill. Tirzepatide is only available as an injection. Oral GLP-1 alternatives include the Wegovy pill and orforglipron.

The Wegovy pill: what it is, how it works, and when it’s coming to the UK

Weight-loss medications

The Wegovy pill: what it is, how it works, and when it’s coming to the UK

The Wegovy pill (oral semaglutide 25 mg) is the first GLP-1 tablet approved for weight loss. FDA-approved in the US, UK availability is expected late 2026.

Can I take Mounjaro or Wegovy with my condition?

Weight-loss medications

Can I take Mounjaro or Wegovy with my condition?

Free tool to check if your health conditions or medications are compatible with Mounjaro or Wegovy. Based on UK prescribing guidelines. No sign-up needed.

GLP-1 meal plan generator | Mounjaro and Wegovy

Weight-loss medications

GLP-1 meal plan generator | Mounjaro and Wegovy

Free GLP-1 meal plan generator for Mounjaro & Wegovy. Creates personalised weekly plans from 687 recipes with high-protein and nausea-friendly options.

Make losing weight feel Second Nature

The first step on your Second Nature journey is to take our health quiz.

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