Weight-loss medications
Evidence-based guidance on weight-loss medications including GLP-1 receptor agonists like Wegovy, Ozempic, and Mounjaro. Find reliable information on efficacy, side effects, NHS availability, and how these medications work as part of a balanced approach to weight loss. Our content is developed by healthcare professionals and nutritionists to support informed decisions about medication-assisted weight loss in the UK.
Weight-loss medications
CagriSema vs Mounjaro: how they compare on weight loss, side effects, and UK availability
Mounjaro produced more weight loss than CagriSema in REDEFINE 4: 25.5% vs 23.0% over 84 weeks. Only Mounjaro is licensed and available in the UK.
Weight-loss medications
What is CagriSema? A UK guide to Novo Nordisk’s new weight-loss injection
CagriSema: 22.7% weight loss in REDEFINE 1, the highest for any Novo Nordisk obesity drug. Lost head-to-head to Mounjaro. Not yet UK-approved.
Weight-loss medications
When will CagriSema be available in the UK?
CagriSema isn't yet available in the UK. No MHRA filing as of May 2026. Private launch likely 2026-2027, NHS access from 2028.
Wegovy compatibility
Can you take Wegovy with rheumatoid arthritis?
You can take Wegovy with rheumatoid arthritis. Find out how it interacts with RA medications and why weight loss may improve disease activity.
Wegovy compatibility
Can you take Wegovy if you have chronic kidney disease (CKD)?
You can take Wegovy with chronic kidney disease. Find out which stages are safe, how to monitor, and why it may protect kidney function.
Wegovy compatibility
Can you take Wegovy after a gastric band?
You can take Wegovy after a gastric band, but the combination needs medical supervision. Find out what to expect from your bariatric team and GP.
Wegovy compatibility
Can you take Wegovy with fibromyalgia?
Wegovy is safe to take with fibromyalgia. What the evidence shows on weight loss, pain, and fatigue, plus practical guidance for managing both.
Mounjaro compatibility
Can you take Mounjaro while pregnant?
Mounjaro isn't recommended in pregnancy. UK guidance, the evidence on inadvertent exposure, and how to plan stopping safely before conceiving.
Wegovy compatibility
Can you take Wegovy while pregnant?
Wegovy and pregnancy: UK guidance says stop two months before trying to conceive. What the evidence shows and how to plan it safely.
Weight-loss medications
GLP-1 calorie calculator: how many calories should you eat on Mounjaro or Wegovy?
Use our free GLP-1 calorie calculator to get a daily calorie and protein target, plus how to reach it without counting using the balanced plate.
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