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After transformation
Before transformation

Before

After

Treatment

Transform your health with medical weight loss support

Starting at £99
How it works

Our unique approach

We use medication to create space for change and behaviour science to make it last.

Silence food noise

Reduce appetite and constant food thoughts, giving you the mental space to make more conscious, healthier choices.

Retrain your brain

Daily guidance, simple tools, and expert support help you understand your eating patterns and gradually change them.

Maintain results for life

We focus on helping you to build more sustainable habits that fit into, and enhance, your everyday life, not restrict it.

Medication

A tool to kickstart change

Our clinicians help you choose the right option, monitor side effects, and track progress.

Lose up to 19kg in 12 months

That's 19.1% of your body weight

What is weight loss medication?

Weight-loss medications like Mounjaro (tirzepatide) and Wegovy (semaglutide) are prescription treatments that help regulate appetite and support long-term weight loss.

They work by targeting the same hormones your body uses to manage hunger, fullness, and blood sugar, making it easier to eat less, feel satisfied sooner, and build healthier habits.

What's the difference between Mounjaro and Wegovy?

Both medications work by calming the appetite and helping you feel full sooner, but they act on slightly different hormones in the body.

Wegovy (semaglutide) works on one hormone pathway: GLP-1. This helps reduce hunger, slow digestion, and steady blood sugar.

Mounjaro (tirzepatide) works on two hormone pathways: GIP + GLP-1. This combined effect can lead to stronger appetite control and, for many people, greater weight loss.

What this means in practice:
Both medicines are effective for weight loss, but Mounjaro tends to produce more consistent and higher average weight loss in clinical trials. Average weight loss can reach 20–25% of body weight with Mounjaro, compared with up to 19.1% with Wegovy.

Is it safe?

Yes, when prescribed responsibly and monitored by a qualified clinician.
GLP-1 medications are well-studied, with strong safety records from long-term clinical trials.

However, like all medications, they aren't suitable for everyone. That's why we complete a detailed health assessment before prescribing.

Weight loss is complicated

You don’t need to figure it out alone anymore

Our team of doctors, psychologists, and dietitians guide your journey

Rosie Carr

Rosie Carr

Dietitian (MDiet)

Dr Rachel Hall

Dr Rachel Hall

Doctor (MBCHB Oxon)

Dr Becky Richards

Dr Becky Richards

Psychologist

What to expect

Here's everything you'll get
with your programme

Second Nature health kit box

Your FREE health kit

Enjoy 100+ nutritious recipes and bluetooth scales with your first order.

Bluetooth scales
Recipe cookbook
Wegovy pen
Second Nature App

The Second Nature App

Designed by psychologists.
Recommended by GPs. Used by the NHS.

Apple App Store

4.8

out of 5
6.2K Ratings

Break old habits and thought patterns to build lasting healthy habits

Handy tools and resources to support a healthy lifestyle and mindset

Improve your relationship with food. No deprivation or obsessive thoughts

Celebrate your progress. Track habits, weight, steps and sleep improvements

Woman Listening

More than just a jab

The medication alone is not enough, we offer comprehensive human support so you're never left feeling stuck or alone.

Clinical oversight

Clinical oversight

Your clinician reviews your progress and plan each month.

1-1 health coaching

1-1 health coaching

Get personalised guidance on side effects and nutrition.

Customer support

Customer support

Our team is here to help with any technical issues or concerns.

Peer community

Peer community

Connect with others on a similar journey to you.

Member Stories

Join thousands of our members transforming their health

Trustpilot rating
Anneka W. before

Day 1

Anneka W. after

Month 9

Anneka lost 38 kg

"I feel like I'm back to my old self, and I'm showing my kids and grandkids a different example."

Anneka W.

Steven W. before

Day 1

Steven W. after

Month 12

Steven lost 32 kg

"Nothing else worked for me until Second Nature. My clothes have gone from 5XL to Large."

Steven W.

Ann W. before

Day 1

Ann W. after

Month 9

Ann lost 19 kg

"After years of struggling to lose weight and always feeling uncomfortable in my body. I have finally found something that works for me."

Ann W.

Supporting you

Speak to someone

Mike Gibbs

Mike Gibbs

Co-founder and COO

Book a call with our support team to talk through any questions or concerns you have. We're here to help.

FAQs

What is weight loss medication?

Weight-loss medications like Mounjaro (tirzepatide) and Wegovy (semaglutide) are prescription treatments that help regulate appetite and support long-term weight loss.

They work by targeting the same hormones your body uses to manage hunger, fullness, and blood sugar, making it easier to eat less, feel satisfied sooner, and build healthier habits.

What's the difference between Mounjaro and Wegovy?

Both medications work by calming the appetite and helping you feel full sooner, but they act on slightly different hormones in the body.

Wegovy (semaglutide) works on one hormone pathway: GLP-1. This helps reduce hunger, slow digestion, and steady blood sugar.

Mounjaro (tirzepatide) works on two hormone pathways: GIP + GLP-1. This combined effect can lead to stronger appetite control and, for many people, greater weight loss.

What this means in practice:
Both medicines are effective for weight loss, but Mounjaro tends to produce more consistent and higher average weight loss in clinical trials. Average weight loss can reach 20–25% of body weight with Mounjaro, compared with up to 19.1% with Wegovy.

Is it safe?

Yes, when prescribed responsibly and monitored by a qualified clinician.
GLP-1 medications are well-studied, with strong safety records from long-term clinical trials.

However, like all medications, they aren't suitable for everyone. That's why we complete a detailed health assessment before prescribing.

Is the medication safe with my existing conditions (HRT, thyroid issues, previous gallbladder removal)?

We can't give you a yes or no without completing our health assessment; the clinical prescribing clinician will evaluate your individual situation.

Previous gallbladder removal, certain thyroid conditions, and other health issues require careful consideration but in many circumstances, you can take Mounjaro alongside these conditions. HRT typically isn't a problem.

The onboarding includes a detailed health questionnaire and clinical review. Be completely honest about your health history.

What happens when I stop taking the medication? Will I regain weight?

It depends on the habits you've built while on medication. Research shows people typically regain two-thirds of lost weight without proper support.

Our data suggests something different: participants who develop sustainable habits with our programme show only 3.2% weight regain after stopping, compared to 6%+ without support.

We focus on building these habits from day one; when appetite is lower and it's easier to learn what healthy eating actually looks and feels like.

The medication gives you a window to change your relationship with food, not just lose weight temporarily.

What support do I get from my health coach? How do I communicate with them?

Your health coach is a UK-registered dietitian or nutritionist, available 5 days a week through the app. You message them directly and get responses typically same day.

They help with managing side effects, adjusting eating habits as your appetite changes, and building practical skills around food. You're also placed in a small group with others on similar journeys for peer support.

The support continues throughout your programme, not just at the start.

Can I stay on a lower dose if it's working for me?

Yes, you can stay on a dose that's working well for you.

Some people find excellent results at 5 mg or 7.5 mg of Mounjaro and choose to stay there.

Others need to gradually move up to 15 mg. The clinical team will work with you to find what's right based on your weight loss, side effects, and goals.

It's not one-size-fits-all; the decision is made together with the clinical team.

Can I switch to Second Nature from another provider and keep my current dose?

Yes, in most cases you can continue your current dose after a clinical assessment.

Our prescribing pharmacists will review your current medication, how long you've been taking it, and your medical history. If you're stable and everything checks out medically, you can typically continue rather than starting from the beginning.

You'll complete a health questionnaire and have a consultation with our clinical team, then get access to the full programme alongside your medication.

Can I cancel or pause at any time? Am I locked into a contract?

You can cancel anytime with no penalties or long-term contract.

If you're thinking about cancelling because of side effects, cost, or feeling stuck, it's worth speaking to your health coach first - they might be able to help.

How do I get help if I experience severe side effects?

For mild side effects like nausea or constipation, message your health coach.

For moderate or persistent issues, they'll escalate to the clinical team. For severe symptoms (severe abdominal pain, allergic reactions), contact 111 or go to A&E immediately; don't wait to message us first.

Common side effects typically improve over time. Our research showed 69% of participants reported no side effects by month 12.

Who is your clinical team? Are they qualified doctors?

Our prescribing team are independent prescribing pharmacists registered with the General Pharmaceutical Council. They handle all medication decisions and clinical oversight.

Your health coaches are UK-registered dietitians or nutritionists with specialist training in GLP-1 medications. Dr Rachel Hall (MBChB) provides medical review and oversight.

How is Second Nature different from other providers?

We've had the privilege of working with the NHS for over eight years, helping people across the UK take meaningful steps toward a healthier, happier life.

Our programmes are designed to meet people where they are, whether that means support with weight loss through compassionate one-to-one health coaching, or access to the latest weight-loss medications (like Mounjaro and Wegovy) delivered alongside expert care from a multidisciplinary team of doctors, psychologists, dietitians, and personal trainers.

At the heart of everything we do is a simple belief: real, lasting change comes from building better habits, not relying on quick fixes. We're here to support that change every step of the way.

With over a decade of experience, thousands of lives changed, and a long-standing record of delivering programmes used by the NHS, we believe we're the UK's most trusted weight-loss programme.

We hope to offer you something invaluable: peace of mind, and the support you need to take that first step.